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Titolo:
Micrometastasis to in-transit lymph nodes from extremity and truncal malignant melanoma
Autore:
Thelmo, MC; Morita, ET; Treseler, PA; Nguyen, LH; Allen, RE; Sagebiel, RW; Kashani-Sabet, M; Leong, SPL;
Indirizzi:
Univ Calif San Francisco, Dept Surg, Sentinel Lymph Node Program, Med Ctr,San Francisco, CA 94115 USA Univ Calif San Francisco San Francisco CA USA 94115 ancisco, CA 94115 USA Univ Calif San Francisco, Med Ctr, Dept Nucl Med, San Francisco, CA 94115 USA Univ Calif San Francisco San Francisco CA USA 94115 ancisco, CA 94115 USA Univ Calif San Francisco, Med Ctr, Dept Pathol, San Francisco, CA 94115 USA Univ Calif San Francisco San Francisco CA USA 94115 ancisco, CA 94115 USA Univ Calif San Francisco, Med Ctr, Melanoma Ctr, San Francisco, CA 94115 USA Univ Calif San Francisco San Francisco CA USA 94115 ancisco, CA 94115 USA
Titolo Testata:
ANNALS OF SURGICAL ONCOLOGY
fascicolo: 5, volume: 8, anno: 2001,
pagine: 444 - 448
SICI:
1068-9265(200106)8:5<444:MTILNF>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
PREOPERATIVE LYMPHOSCINTIGRAPHY; CUTANEOUS MELANOMA; NODAL METASTASES; SENTINEL; DRAINAGE;
Keywords:
melanoma; micrometastasis; in-transit sentinel lymph node;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Leong, SPL Univ Calif San Francisco, Dept Surg, Sentinel Lymph Node Program, Med Ctr,1600 Divisadero St,Suite C333, San Francisco, CA 94115 USA Univ Calif San Francisco 1600 Divisadero St,Suite C333 San Francisco CA USA 94115
Citazione:
M.C. Thelmo et al., "Micrometastasis to in-transit lymph nodes from extremity and truncal malignant melanoma", ANN SURG O, 8(5), 2001, pp. 444-448

Abstract

Background: The sentinel lymph node (SLN) is the first lymph node in the regional nodal basin to receive metastatic cells. In-transit nodes are foundbetween the primary melanoma site and regional nodal basins. To date, thisis one of the first reports on micrometastasis to in-transit nodes. Methods: Retrospective database and medical records were reviewed from October 21, 1993, to November 19, 1999. At the UCSF Melanoma Center, patients with tumor thickness >1 min or <1 mm with high-risk features are managed with preoperative lymphoscintigraphy, selective SLN dissection, and wide local excision. Results: Thirty (5%) out of 557 extremity and truncal melanoma patients had in-transit SLNs, Three patients had positive in-transit SLs, and negativeSLNs in the regional nodal basin. Two patients had positive in-transit andregional SLNs. Three patients had negative in-transit SLNs but positive regional SLNs. The remaining 22 patients were negative for in-transit and regional SLNs. Conclusions: In-transit SLNs may harbor micrometastasis. About 10% of the time, micrometastasis may involve the in-transit and not the regional SLN. Therefore, both in-transit and regional SLNs should be harvested.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 22:31:24