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Titolo:
Impact of splenectomy for lymph node dissection on long-term surgical outcome in gastric cancer
Autore:
Lee, KY; Noh, SH; Hyung, WJ; Lee, JH; Lah, KH; Choi, SH; Min, JS;
Indirizzi:
Yonsei Univ, Coll Med, Dept Surg, Seoul, South Korea Yonsei Univ Seoul South Korea , Coll Med, Dept Surg, Seoul, South Korea Yonsei Univ, Coll Med, Canc Metastasis Res Ctr, Seoul, South Korea Yonsei Univ Seoul South Korea nc Metastasis Res Ctr, Seoul, South Korea
Titolo Testata:
ANNALS OF SURGICAL ONCOLOGY
fascicolo: 5, volume: 8, anno: 2001,
pagine: 402 - 406
SICI:
1068-9265(200106)8:5<402:IOSFLN>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
TOTAL GASTRECTOMY; CARCINOMA; SURVIVAL; SURGERY; MORBIDITY;
Keywords:
splenectomy; lymph node dissection; long-term outcome; gastric cancer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Noh, SH Yonsei Univ, Coll Med, Dept Surg, CPO Box 8044, Seoul, South KoreaYonsei Univ CPO Box 8044 Seoul South Korea 4, Seoul, South Korea
Citazione:
K.Y. Lee et al., "Impact of splenectomy for lymph node dissection on long-term surgical outcome in gastric cancer", ANN SURG O, 8(5), 2001, pp. 402-406

Abstract

Background: In the treatment of gastric cancer, splenectomy is performed for effective lymph. node dissection around the splenic artery and splenic hilum. The purpose of this study was to clarify the long-term outcome of splenectomy in the treatment of gastric cancer. Methods: The effect of splenectomy on recurrence and prognosis was examined in a retrospective analysis of 665 patients who had undergone curative total gastrectomy for gastric carcinoma from 1987 to 1996. The risk factors associated with recurrence and prognosis were investigated by univariate andmultivariate analysis. Results: The splenectomy group showed more advanced lesions and a higher recurrence rate than the spleen-preserved group. However, after adjusting for the TNM (tumor, node, metastasis) stage, there was no significant difference in recurrence rate and pattern between the two groups. Logistic regression analysis revealed that gross type, serosal invasion, and nodal metastasis were independent risk factors for recurrence while splenectomy was not. When comparing patients with the same TNM (tumor, node, metastasis) stages,no significant difference in the 5-year survival rates was apparent. Multivariate analysis demonstrated that age, serosal invasion, and nodal metastasis were independent prognostic factors whereas splenectomy was not. Conclusions: These data suggest that splenectomy for lymph node dissectionin gastric cancer is not effective regarding long-term patient prognosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/10/20 alle ore 05:27:32