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Titolo:
Positron emission tomography (PET) and other nuclear medicine modalities in staging gastrointestinal cancer
Autore:
Bombardieri, E; Aliberti, G; De Graaf, C; Pauwels, E; Crippa, F;
Indirizzi:
Ist Nazl Tumori, Div Nucl Med, PET Ctr, I-20133 Milan, Italy Ist Nazl Tumori Milan Italy I-20133 l Med, PET Ctr, I-20133 Milan, Italy
Titolo Testata:
SEMINARS IN SURGICAL ONCOLOGY
fascicolo: 2, volume: 20, anno: 2001,
pagine: 134 - 146
SICI:
8756-0437(200103)20:2<134:PET(AO>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
SOMATOSTATIN RECEPTOR SCINTIGRAPHY; RECURRENT COLORECTAL-CANCER; VASOACTIVE-INTESTINAL-PEPTIDE; COST-EFFECTIVENESS ANALYSIS; F-18 FLUORODEOXYGLUCOSE; NEUROENDOCRINE TUMORS; PANCREATIC-CANCER; LIVER METASTASES; FDG-PET; HEPATOCELLULAR-CARCINOMA;
Keywords:
positron emission tomography (PET); emission-computed; radionuclide imaging; receptors; somatostatin; gastrointestinal neoplasms;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
125
Recensione:
Indirizzi per estratti:
Indirizzo: Bombardieri, E Ist Nazl Tumori, Div Nucl Med, PET Ctr, Via Venezian 1, I-20133 Milan, Italy Ist Nazl Tumori Via Venezian 1 Milan Italy I-20133 , Italy
Citazione:
E. Bombardieri et al., "Positron emission tomography (PET) and other nuclear medicine modalities in staging gastrointestinal cancer", SEM SURG ON, 20(2), 2001, pp. 134-146

Abstract

Gastrointestinal (GI) cancers account for the second highest number of newtumor cases and deaths per year in the United States and Western Europe. The most frequently involved sites are, in descending order, the colorectum,stomach, pancreas, liver, bile duct, and esophagus. The most common tumor type is adenocarcinoma. Among the epithelial cancers, great attention has recently been given to the tumors of neuroendocrine origin. These concepts are relevant because nuclear medicine imaging is based on visualization by means of a particular uptake of radiolabelled tracers in cancer cells that concentrate the radioactive signal. This signal is detected and reconstructed in planar or tomographic images. Different radiopharmaceuticals have beenproposed for diagnostic application in oncology (such as radiolabelled monoclonal antibodies (MAbs), receptor tracers, and positron-emitting radiopharmaceuticals), and they are currently used as tracers for tumor detection with different modalities and techniques. Most of these techniques demonstrate their clinical usefulness in the diagnosis of GI cancer. This work is not intended to be a comprehensive review of all the extensive experience andpossibilities of nuclear medicine for the diagnosis of GI tumors; rather, it aims to summarize the current status of the most important approaches and their main indications in staging GI cancers. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/10/20 alle ore 14:48:04