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Titolo:
Synthesis of some new 4,5-dihydro-3(2H)pyridazinone and 3(2H)pyridazinone with potential cardiotonic activity
Autore:
Dumitrascu, F; Mitan, CI; Draghici, C; Caproiu, MT;
Indirizzi:
Acad Romana, Inst Chim Organ CD Nenitescu, Bucharest 71141, Romania Acad Romana Bucharest Romania 71141 Nenitescu, Bucharest 71141, Romania
Titolo Testata:
REVISTA DE CHIMIE
fascicolo: 4, volume: 52, anno: 2001,
pagine: 193 - 198
SICI:
0034-7752(200104)52:4<193:SOSN4A>2.0.ZU;2-1
Fonte:
ISI
Lingua:
RUM
Soggetto:
PIMOBENDAN;
Keywords:
4-arylidene-4,5-dihydro-3(2H)pyridazinones; cyanoethylation; H-1- and C-13-NMR spectra;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Engineering, Computing & Technology
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Dumitrascu, F Acad Romana, Inst Chim Organ CD Nenitescu, Splaiul Independentei 202B, Bucharest 71141, Romania Acad Romana Splaiul Independentei 202B Bucharest Romania 71141
Citazione:
F. Dumitrascu et al., "Synthesis of some new 4,5-dihydro-3(2H)pyridazinone and 3(2H)pyridazinone with potential cardiotonic activity", REV CHIM, 52(4), 2001, pp. 193-198

Abstract

New 4-arylidene-4,5-dihydro-3(2H)pyridazinones (9) were obtained by condensation of 6-substituted-4,5-dihydro-3(2H)pyridazinones (7) with aroma tic aldehydes. The N-cyanoethylation of (7) and of 3(2H)pyridazinones (8) was performed with acrylonitrile in the presence of potassium carbonate, giving the compounds (10) and (11), respectively. The H-1- and C-13-NMR data of compounds (9), (10) and (11) are reported.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/10/20 alle ore 07:42:18