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Titolo:
Mechanical ventilation in children with severe asthma
Autore:
Malmstrom, K; Kaila, M; Korhonen, K; Dunder, T; Nermes, M; Klaukka, T; Sarna, S; Juntunen-Backman, K;
Indirizzi:
Univ Helsinki, Dept Publ Hlth, Helsinki, Finland Univ Helsinki Helsinki Finland sinki, Dept Publ Hlth, Helsinki, Finland Turku Univ, Cent Hosp, Dept Pediat, Turku, Finland Turku Univ Turku Finland u Univ, Cent Hosp, Dept Pediat, Turku, Finland Oulu Univ Hosp, Dept Pediat, Oulu, Finland Oulu Univ Hosp Oulu FinlandOulu Univ Hosp, Dept Pediat, Oulu, Finland Kuopio Univ Hosp, Dept Pediat, SF-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland SF-70210 ediat, SF-70210 Kuopio, Finland Tampere Univ Hosp, Dept Pediat, Tampere, Finland Tampere Univ Hosp Tampere Finland v Hosp, Dept Pediat, Tampere, Finland Univ Helsinki, Cent Hosp, Dept Pediat, Helsinki, Finland Univ Helsinki Helsinki Finland ent Hosp, Dept Pediat, Helsinki, Finland
Titolo Testata:
PEDIATRIC PULMONOLOGY
fascicolo: 6, volume: 31, anno: 2001,
pagine: 405 - 411
SICI:
8755-6863(200106)31:6<405:MVICWS>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTENSIVE-CARE UNIT; CHILDHOOD ASTHMA; RESPIRATORY-FAILURE; TRENDS; EXPERIENCE; MORTALITY; HOSPITALIZATION; ADMISSIONS; MANAGEMENT; PREVALENCE;
Keywords:
children; intensive care; mortality; asthma; mechanical ventilation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Malmstrom, K Univ Helsinki, Cent Hosp, Hosp Children & Adolescents, POB 281, SF-00029 Helsinki, Finland Univ Helsinki POB 281 Helsinki Finland SF-00029 nki, Finland
Citazione:
K. Malmstrom et al., "Mechanical ventilation in children with severe asthma", PEDIAT PULM, 31(6), 2001, pp. 405-411

Abstract

Hospital admissions for childhood asthma have increased during the past few decades. The aim of this study was to describe the need for mechanical ventilation for severe asthma exacerbation in children in Finland from 1976 to 1995. We reviewed medical records and collected data retrospectively fromall 5 university hospitals in Finland, thus covering the entire populationof about 5 million. The endpoints selected were the number of admissions and readmissions leading to mechanical ventilation, duration of stay in the hospital, and mortality. Moreover, asthma medications prescribed prior to admission and administered in the intensive care unit (ICU), as well as the etiology of the exacerbation associated with mechanical Ventilation were examined. Mechanical ventilation was required in 66 ICU admissions (59 patients). This constituted approximately 10% of all 632 admissions for acute asthma to an ICU. The number of admissions decreased from 1976 to 1995: 41 admissionsbetween 1976 and 1985 vs. 25 admissions during the next 10-year period. The mean age at admission to the ICU was 3.6 years, and 46% of the patients were boys. Prior to the index admission, 70% of the patients had used asthmamedication such as oral bronchodilator (50%), inhaled bronchodilator (20%), theophylline (38%), inhaled glucocorticoid (18%), oral glucocorticoid (5%), and cromoglycate (7%). Respiratory infection was by far the most common cause of all the exacerbations (61%), followed by food allergy (8%) and gastroesophageal reflux (3%). In 28% of cases the cause of the severe asthma exacerbation could not be identified. In the mechanically ventilated patients readmissions occurred 38 times between 1976 and 1985 vs. 5 times between 1986 and 1995. Five of the patients who received mechanical ventilation died, and in 3 of these patients asthma was the event causing death. In conclusion, there has been decrease in the number of first and repeat ICU admission for asthma requiring mechanical Ventilation between 1970 and 1995. This trend occurred despite a simultaneous 5% yearly increase in hospital admissions for childhood asthma during these 2 decades. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 23:02:26