Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Experimental and theoretical analysis of phase singularity dynamics in cardiac tissue
Autore:
Bray, MA; Lin, SF; Aliev, RR; Roth, BJ; Wikswo, JP;
Indirizzi:
Vanderbilt Univ, Dept Biomed Engn, Nashville, TN 37235 USA Vanderbilt Univ Nashville TN USA 37235 omed Engn, Nashville, TN 37235 USA Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA Vanderbilt Univ Nashville TN USA 37235 & Astron, Nashville, TN 37235 USA Oakland Univ, Dept Phys, Rochester, MI USA Oakland Univ Rochester MI USAOakland Univ, Dept Phys, Rochester, MI USA
Titolo Testata:
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
fascicolo: 6, volume: 12, anno: 2001,
pagine: 716 - 722
SICI:
1045-3873(200106)12:6<716:EATAOP>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPIRAL WAVES; REENTRANT ACTIVITY; MECHANISM; MEDIA; STIMULATION; MYOCARDIUM; MUSCLE;
Keywords:
nonlinear dynamics; arrhythmia; phase singularity; topologic charge; optical imaging; cardiac reentry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Bray, MA Vanderbilt Univ, Dept Biomed Engn, 5824 Stevenson Ctr, Nashville,TN 37235USA Vanderbilt Univ 5824 Stevenson Ctr Nashville TN USA 37235 7235USA
Citazione:
M.A. Bray et al., "Experimental and theoretical analysis of phase singularity dynamics in cardiac tissue", J CARD ELEC, 12(6), 2001, pp. 716-722

Abstract

Introduction: Quantitative analysis of complex self-excitatory wave patterns, such as cardiac fibrillation and other high-order reentry, requires thedevelopment of new tools for identifying and tracking the most important features of the activation, such as phase singularities. Methods and Results: Image processing operations can be used to detect thephase singularity at the tip of a spiral wave. The phase space behavior ofa spatiotemporal sequence of data may be reconstructed using time-series analysis. The phase singularities then are localized efficiently by computing the topologic charge density as the curl of the spatial phase gradient, We analyzed the singularity interaction dynamics of both experimentally observed and numerically simulated instances of quatrefoil reentry and found that the singularity behavior in the experimental preparations can be classified into three categories on the basis of how their separation changes withtime. Conclusion: Topologic charge densities can be calculated easily and efficiently to reveal phase singularity behavior. However, the differences between theoretical and experimental observations of singularity separation distances indicate the need for more sophisticated numerical models.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 08:19:14