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Titolo:
Drug abuse and bipolar disorder: comorbidity or misdiagnosis?
Autore:
Brown, ES; Suppes, T; Adinoff, B; Thomas, NR;
Indirizzi:
Univ Texas, SW Med Ctr, Dept Psychiat, Dallas, TX 75390 USA Univ Texas Dallas TX USA 75390 d Ctr, Dept Psychiat, Dallas, TX 75390 USA Dallas Vet Affairs Med Ctr, Psychiat Serv, Dallas, TX USA Dallas Vet Affairs Med Ctr Dallas TX USA , Psychiat Serv, Dallas, TX USA
Titolo Testata:
JOURNAL OF AFFECTIVE DISORDERS
fascicolo: 2, volume: 65, anno: 2001,
pagine: 105 - 115
SICI:
0165-0327(200107)65:2<105:DAABDC>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
MANIC-DEPRESSIVE ILLNESS; SUBSTANCE USE DISORDER; COCAINE ABUSERS; MENTALLY-ILL; PSYCHIATRIC-DIAGNOSIS; INTRAVENOUS COCAINE; SERVICE UTILIZATION; BETA-ENDORPHIN; CORTICOSTERONE; AMPHETAMINE;
Keywords:
bipolar disorder; substance abuse; mood stabilizers; neuroleptics;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
100
Recensione:
Indirizzi per estratti:
Indirizzo: Brown, ES Univ Texas, SW Med Ctr, Dept Psychiat, 5323 Harry Hines Blvd, Dallas, TX 75390 USA Univ Texas 5323 Harry Hines Blvd Dallas TX USA 75390 X 75390 USA
Citazione:
E.S. Brown et al., "Drug abuse and bipolar disorder: comorbidity or misdiagnosis?", J AFFECT D, 65(2), 2001, pp. 105-115

Abstract

Bipolar disorder is a common, severe and cyclic psychiatric illness. A strong association between alcohol dependence and bipolar disorder has been reported in numerous studies. The abuse of other drugs including cocaine, amphetamines, opiates, cannabis, and prescription medications in bipolar patients is also an important public health concern and has been less extensively investigated. This review examines the abuse of drugs other than alcohol or nicotine in people with bipolar disorder. The high rates of milder affective symptoms but not mania observed in patients in drug abuse treatment settings suggests the symptoms may in many cases be associated with the drug use. However, such patients presenting in psychiatric settings might be suffering from cyclothymic and related attenuated bipolar disorders (type LI). Substance abuse may be associated with medication non-compliance, more mixed or dysphoric mania and possibly an earlier onset of affective symptoms and more hospitalizations. The pharmacotherapy of patients with bipolar disorder and drug abuse is examined, including evidence on the use of mood stabilizers, neuroleptics and the newer atypical antipsychotics in this population. (C) 2001 Elsevier Science B.V. All rights reserved.

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Documento generato il 21/01/20 alle ore 00:59:21