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Titolo:
Correlation of optic nerve head tomography with visual field sensitivity in papilledema
Autore:
Salgarello, T; Falsini, B; Tedesco, S; Galan, ME; Colotto, A; Scullica, L;
Indirizzi:
Catholic Univ Sacred Heart, Ist Oftalmol, I-00168 Rome, Italy Catholic Univ Sacred Heart Rome Italy I-00168 almol, I-00168 Rome, Italy
Titolo Testata:
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
fascicolo: 7, volume: 42, anno: 2001,
pagine: 1487 - 1494
SICI:
0146-0404(200106)42:7<1487:COONHT>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
IDIOPATHIC INTRACRANIAL HYPERTENSION; SCANNING LASER TOMOGRAPHY; HEIDELBERG-RETINA-TOMOGRAPH; TEST-RETEST VARIABILITY; PSEUDOTUMOR CEREBRI; TOPOGRAPHIC MEASUREMENTS; PATTERN ELECTRORETINOGRAM; OCULAR HYPERTENSION; PERIMETRY; REPRODUCIBILITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Salgarello, T Catholic Univ Sacred Heart, Ist Oftalmol, Lgo F Vito 1, I-00168 Rome, Italy Catholic Univ Sacred Heart Lgo F Vito 1 Rome Italy I-00168
Citazione:
T. Salgarello et al., "Correlation of optic nerve head tomography with visual field sensitivity in papilledema", INV OPHTH V, 42(7), 2001, pp. 1487-1494

Abstract

PURPOSE. To quantify the relationship between optic nerve head tomography and perimetric sensitivity in patients with papilledema. METHODS. Eight patients with variable degrees of recently diagnosed papilledema associated with idiopathic intracranial hypertension OIH) were evaluated with confocal scanning laser ophthalmoscopy (CSLO) and automated perimetry. Patients were followed up with serial measurements over a period of 5 to 30 months (mean +/- SD, 17.1 +/- 9), while under medical treatment (acetazolamide). The tomographic parameters, volume above reference (VAR), volume above surface (VAS), effective mean height (EMH), and maximum height in contour MxHC), were obtained by tomography, either globally or from predefined disc sectors. The perimetric indices, mean deviation (MD) and pattern SD(PSD), were evaluated. The results from patients' right eyes and the individual intereye differences in both tomographic and perimetric parameters, were statistically evaluated by nonparametric correlational (Spearman) and repeated measures (Wilcoxon) analyses. RESULTS. At baseline, all tomographic parameters were negatively correlated with MD in global (r = -0.8) and sectorial (r = -0.6) evaluations. The interocular differences in overall tomographic parameters were correlated with corresponding differences in perimetric MD (r = -0.8) and PSD (r = 0.6). During the follow-up period, volumetric disc parameters decreased (P < 0.02), whereas perimetric MD increased (P = 0.02) at comparable times. CONCLUSIONS. In patients with recently diagnosed papilledema, optic nerve head tomographic abnormalities are quantitatively correlated with visual field sensitivity losses. Therapeutic improvement of volumetric parameters may be paralleled by recovery in perimetric sensitivity. The data support thepossible use of both techniques in combination to monitor the amount of papilledema and the effectiveness of treatments designed to reduce intracranial hypertension.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 08:04:22