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Titolo:
Diagnosis of vascular dementia and Alzheimer's disease
Autore:
Roman, G;
Indirizzi:
Univ Texas, Hlth Sci Ctr, San Antonio, TX 78284 USA Univ Texas San Antonio TX USA 78284 th Sci Ctr, San Antonio, TX 78284 USA
Titolo Testata:
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
, , anno: 2001, supplemento:, 120
pagine: 9 - 13
SICI:
1368-5031(200105):<9:DOVDAA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
COGNITIVE IMPAIRMENT; CLINICAL-CRITERIA;
Keywords:
Alzheimer's disease; diagnosis; vascular dementia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Roman, G Univ Texas, Hlth Sci Ctr, 7703 Floyd Curl Dr, San Antonio, TX 78284 USA Univ Texas 7703 Floyd Curl Dr San Antonio TX USA 78284 78284 USA
Citazione:
G. Roman, "Diagnosis of vascular dementia and Alzheimer's disease", INT J CL PR, 2001, pp. 9-13

Abstract

Vascular dementia (VaD) and Alzheimer's disease are sometimes difficult todistinguish due to overlaps in symptomatology, pathophysiology and comorbidity. The issue of differential diagnosis is further complicated by the fact that many patients have concomitant Alzheimer's disease and cerebrovascular disease (CVD) ('mixed' dementia). Each pathology may contribute to varying degrees, giving rise to a continuum of patients in whom pure CVD and pure Alzheimer's disease represent the two extremes. Despite the clear overlapbetween the conditions, and the prevalence of 'mixed' dementia, a number of criteria for Alzheimer's disease and VaD do not make provision for 'mixed' dementia distinct from the coincidence of any two other dementing illnesses. We will discuss the current diagnostic criferia for VaD, with or without coexisting Alzheimer's disease, in an effort to determine how best to diagnose VaD. These include traditional criferia such as the Diagnostic and Statistical Manual of Mental Disorders or the Hachinski Ischemic Scale, and She more recently developed criteria by the California Alzheimer's Disease Diagnostic and Treatment Centers (CAD-DTC) and the National institute of Neurological Disorders and Stroke and the Association Internationale pour la Recherche et l'Enseignement en Neurosciences (NINDS-AIREN) international Workshop. The CAD-DTC and NINDS-AIREN rely on neuroimaging - ideally, every patient suspected of dementia should have brain imaging, but although this ispossible in clinical trials (for which these criferia were designed), if is not always feasible in population-based epidemiological studies and clinical practice in some countries.

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Documento generato il 05/04/20 alle ore 07:06:23