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Titolo:
Sustained postinfarction myocardial oedema in humans visualised by magnetic resonance imaging
Autore:
Nilsson, JC; Nielsen, G; Groenning, BA; Fritz-Hansen, T; Sondergaard, L; Jensen, GB; Larsson, HBW;
Indirizzi:
Univ Copenhagen, Hvidovre Hosp, Danish Res Ctr Magnet Resonance, DK-2650 Hvidovre, Denmark Univ Copenhagen Hvidovre Denmark DK-2650 ance, DK-2650 Hvidovre, Denmark Univ Copenhagen, Hvidovre Hosp, Dept Cardiol, DK-2650 Hvidovre, Denmark Univ Copenhagen Hvidovre Denmark DK-2650 diol, DK-2650 Hvidovre, Denmark
Titolo Testata:
HEART
fascicolo: 6, volume: 85, anno: 2001,
pagine: 639 - 642
SICI:
1355-6037(200106)85:6<639:SPMOIH>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY OCCLUSION; LEFT-VENTRICULAR FUNCTION; CONTRAST ENHANCEMENT; MEMBRANE INJURY; INFARCT SIZE; 1.5 T; REPERFUSION; EDEMA; HEART; SODIUM;
Keywords:
myocardial infarction; myocardial oedema; magnetic resonance imaging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Nilsson, JC Univ Copenhagen, Hvidovre Hosp, Danish Res Ctr Magnet Resonance, Kettegaard Alle 30, DK-2650 Hvidovre, Denmark Univ Copenhagen KettegaardAlle 30 Hvidovre Denmark DK-2650 k
Citazione:
J.C. Nilsson et al., "Sustained postinfarction myocardial oedema in humans visualised by magnetic resonance imaging", HEART, 85(6), 2001, pp. 639-642

Abstract

Objective - To demonstrate postinfarction myocardial oedema in humans withparticular reference to the longitudinal course, using magnetic resonance imaging (MRI). Design - Prospective observational study. Subjects were studied one week, one month, three months, six months, and one year after presenting with a myocardial infarct. Setting - Cardiology and magnetic resonance departments in a Danish university hospital. Patients - 10 patients (three women, seven men), mean (SEM) age 58.2 (3.20) years, with a first transmural myocardial infarct. Main outcome measures - location and duration of postinfarction myocardialoedema. Results - All patients had signs of postinfarction myocardial oedema. The magnetic resonance images were evaluated by two blinded procedures, employing two MRT and two ECG observers: (1) MRI determined oedema location was compared with the ECG determined site of infarction and almost complete agreement was found; (2) the time course of postinfarction myocardial oedema wasexplored semiquantitatively, using an image ranking procedure. Myocardial oedema was greatest at the initial examination one week after the infarction, with a gradual decline during the following months (Spearman's rank correlation analysis: p(observer 1) = 0.94 (p < 0.0001) and p(observer 2) = 0.97 (P < 0.0001)), The median duration of oedema was six months. Conclusions - Postinfarction myocardial oedema seems surprisingly long lasting. This observation is of potential clinical interest because the oedemamay have prognostic significance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 23:47:18