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Titolo:
Effect of a high monounsaturated fatty acid diet on blood pressure and glucose metabolism in women with gestational diabetes mellitus
Autore:
Lauszus, FF; Rasmussen, OW; Henriksen, JE; Klebe, JG; Jensen, L; Lauszus, KS; Hermansen, K;
Indirizzi:
Skejby Hosp, Gynecol Obstet Dept Y, Ctr Diabet & Pregnancy, Skejby, Denmark Skejby Hosp Skejby Denmark t Y, Ctr Diabet & Pregnancy, Skejby, Denmark Aarhus Univ Hosp, Med Dept Diabet & Endocrinol C, DK-8000 Aarhus, Denmark Aarhus Univ Hosp Aarhus Denmark DK-8000 rinol C, DK-8000 Aarhus, Denmark Odense Univ Hosp, Diabet Res Ctr, DK-5000 Odense, Denmark Odense Univ Hosp Odense Denmark DK-5000 Res Ctr, DK-5000 Odense, Denmark
Titolo Testata:
EUROPEAN JOURNAL OF CLINICAL NUTRITION
fascicolo: 6, volume: 55, anno: 2001,
pagine: 436 - 443
SICI:
0954-3007(200106)55:6<436:EOAHMF>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIGH-CARBOHYDRATE DIET; INSULIN SENSITIVITY; NIDDM; RESISTANCE; HYPERTENSION; PREGNANCY;
Keywords:
gestational diabetes; ambulatory blood pressure; monounsaturated fatty acids; glycemic regulation; lipids;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Lauszus, FF Holstebro Hosp, Dept Gynecol & Obstet, DK-7500 Holstebro, Denmark Holstebro Hosp Holstebro Denmark DK-7500 Holstebro, Denmark
Citazione:
F.F. Lauszus et al., "Effect of a high monounsaturated fatty acid diet on blood pressure and glucose metabolism in women with gestational diabetes mellitus", EUR J CL N, 55(6), 2001, pp. 436-443

Abstract

Objective: The effect of a diet rich in monounsaturated fatty acids (MUFA)on blood pressure, glycemic control, lipids and insulin sensitivity was evaluated in women with gestational diabetes mellitus. Design and methods: PL randomized, unpaired diet intervention was performed in 27 women with gestational diabetes mellitus in an outpatient clinic. After randomization the women received either a high-carbohydrate diet (H-CHO) or a high-MUFA diet (H-MUFA) from the 33rd gestational week of pregnancy. Outcome measures were 24 h ambulatory blood pressure, blood lipids, glycemic control and insulin sensitivity estimated by an intravenous glucose tolerance test. Results: The 24 h diastolic blood pressure increased more in the H-CHO group than in the H-MUFA group (P < 0.04). Conclusions: After 5 weeks of treatment with a MUFA-enriched diet. no increase in 24 h diastolic blood pressure and no adverse effects on blood lipids were seen. The favorable effect onthe blood pressure by the MUFA diet is a possible non-medication treatment. The H-MUFA diet had no advantage to the H-CHO diet in ameliorating the decline of insulin sensitivity in third term of pregnancy in GDM. Sponsorship: Sources of support were grants from the Mimi and Victor Larsens Foundation, Nordisk Insulin Foundation, Novo Nordisk Foundation, and theInstitute of Experimental Clinical Research, Aarhus University, Denmark. Aarhus Olie Fabrik A/S, Aarhus, Denmark provided the hybrid sunflower oil. The Danish Medical Research Council provided the statistical assistance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 18:46:40