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Titolo:
Properties of the 15D and EQ-5D utility measures in a community sample of people with epilepsy
Autore:
Stavem, K; Bjornaes, H; Lossius, MI;
Indirizzi:
Cent Hosp Akershus, HELTEF, Fdn Hlth Serv Res, N-1474 Norbyhagen, Norway Cent Hosp Akershus Norbyhagen Norway N-1474 s, N-1474 Norbyhagen, Norway Natl Ctr Epilepsy, N-1303 Sandvika, Norway Natl Ctr Epilepsy Sandvika Norway N-1303 ilepsy, N-1303 Sandvika, Norway Cent Hosp Akershus, Dept Neurol, N-1474 Norbyhagen, Norway Cent Hosp Akershus Norbyhagen Norway N-1474 l, N-1474 Norbyhagen, Norway Cent Hosp Akershus, Dept Med, N-1474 Norbyhagen, Norway Cent Hosp Akershus Norbyhagen Norway N-1474 d, N-1474 Norbyhagen, Norway
Titolo Testata:
EPILEPSY RESEARCH
fascicolo: 2-3, volume: 44, anno: 2001,
pagine: 179 - 189
SICI:
0920-1211(200105)44:2-3<179:POT1AE>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
QUALITY-OF-LIFE; COST-EFFECTIVENESS ANALYSIS; HEALTH-STATE PREFERENCES; WEIGHTED KAPPA; EUROQOL EQ-5D; RELIABILITY; RESPONSIVENESS; STANDARD; QUESTIONNAIRE; COEFFICIENT;
Keywords:
epilepsy; health-related quality of life; health status; utilities;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Stavem, K Cent Hosp Akershus, HELTEF, Fdn Hlth Serv Res, N-1474 Norbyhagen, Norway Cent Hosp Akershus Norbyhagen Norway N-1474 Norbyhagen, Norway
Citazione:
K. Stavem et al., "Properties of the 15D and EQ-5D utility measures in a community sample of people with epilepsy", EPILEPSY R, 44(2-3), 2001, pp. 179-189

Abstract

To perform economic evaluation studies in epilepsy using utilities, such as cost-utility analyses, it is necessary to have reliable and valid instruments for eliciting people's preferences. The objective of this study was toassess the reliability and validity of two multiattribute utility measuresin a community sample of 397 people with epilepsy. We assessed the test-retest reliability of individual questionnaire items and aggregate scores. Additionally, construct validity was assessed by correlating items of the EQ-5D with items of the 15D health status questionnaire, and discriminant validity was assessed by comparing scores for known groups. The test-retest reliabilities for the individual items of the 15D (weighted kappa 0.59-0.90, except mobility with only 0.28) and the EQ-5D (weighted kappa 0.49-0.86) were acceptable. For the composite utility scores the test-retest reliability was better (intraclass correlation coefficient 0.93 for both 15D and the EQ-5D). Spearman's rank correlations between EQ-5D single item scores and corresponding 15D single item scores were high (rho 0.34-0.79) and generally higher than the associations between non-corresponding items. Some EQ-5D and15D items discriminated well between patients according to seizure status,psychiatric comorbidity and working status; less well after antiepileptic drug use and neurologic comorbidity. Both the EQ-5D and 15D were reliable instruments and showed properties supporting the construct validity of both measures. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 12:33:43