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Titolo:
Occurrence of compounds estrogenic to freshwater mussels in surface watersin an Urban area
Autore:
Gagne, F; Marcogliese, DJ; Blaise, C; Gendron, AD;
Indirizzi:
Environm Canada, St Lawrence Ctr, Montreal, PQ H2Y 2E7, Canada Environm Canada Montreal PQ Canada H2Y 2E7 , Montreal, PQ H2Y 2E7, Canada
Titolo Testata:
ENVIRONMENTAL TOXICOLOGY
fascicolo: 3, volume: 16, anno: 2001,
pagine: 260 - 268
SICI:
1520-4081(200106)16:3<260:OOCETF>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
TROUT ONCORHYNCHUS-MYKISS; VITELLOGENIN SYNTHESIS; IN-VITRO; MYTILUS-EDULIS; ESTRADIOL-17-BETA; LIVER; HEPATOCYTES; INDUCTION; SERUM; MODULATION;
Keywords:
environmental estrogens; estradiol-binding sites; vitellins; surface waters; Elliptio complanata;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Gagne, F Environm Canada, St Lawrence Ctr, 105 McGill St, Montreal, PQ H2Y2E7, Canada Environm Canada 105 McGill St Montreal PQ Canada H2Y 2E7 , Canada
Citazione:
F. Gagne et al., "Occurrence of compounds estrogenic to freshwater mussels in surface watersin an Urban area", ENVIRON TOX, 16(3), 2001, pp. 260-268

Abstract

Estrogens play a major role in the sexual differentiation, gonad development, and oocyte growth of most oviparous organisms. They also stimulate vitellogenesis, the formation of high-density glycolipophosphoprotein that serves as an energy source for the developing embryo. Surface waters from the St. Lawrence River, obtained in the vicinity of an urban area (Montreal, Quebec, Canada), were studied with respect to,their estrogenic potential to the freshwater mussel Elliptio complanata. Estrogenicity was measured in water extracts by means of a competitive assay of estradiol binding to cytosolic proteins and by the vitellin-inducing ability of mussel hemolymph following direct extract injection. Surface-water samples drawn downstream of a municipal outfall plume and in a river draining a large farming and agricultural area had high levels of total and fecal coliform bacteria. High levels of estrogen competitors were also found and were able to induce vitellins in injected mussels. Moreover, the estrogen-competing potential of the extracts was found to be significantly correlated with total and fecal coliform bacteria (R = 0.9, p < 0.01) and with the levels of vitellins in the hemolymph (R = 0.62, p = 0.03). The results indicate that water samples drawn from within the municipal effluent plume and from a river draining an agricultural area are estrogenic to freshwater mussels. Thus, the environmental inputs of estrogens are,likely to be associated with human sewage and pesticide products. (C) 2001 by John Wiley & Sons, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 09:21:45