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Titolo:
Opportunities and strategies for introducing pharmacogenetics into early drug development
Autore:
Chamberlain, JC; Joubert, PH;
Indirizzi:
Roche Prod Ltd, Welwyn Garden City AL7 3AY, Herts, England Roche Prod LtdWelwyn Garden City Herts England AL7 3AY Y, Herts, England
Titolo Testata:
DRUG DISCOVERY TODAY
fascicolo: 11, volume: 6, anno: 2001,
pagine: 569 - 574
SICI:
1359-6446(20010601)6:11<569:OASFIP>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLINICAL-TRIALS; METHYLTRANSFERASE; POLYMORPHISMS; POPULATIONS; METABOLISM; GENETICS; MEDICINE; GENOMICS; DISEASE; FUTURE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Chamberlain, JC Roche Prod Ltd, 40 Broadwater Rd, Welwyn Garden City AL7 3AY, Herts, England Roche Prod Ltd 40 Broadwater Rd Welwyn Garden City HertsEngland AL7 3AY
Citazione:
J.C. Chamberlain e P.H. Joubert, "Opportunities and strategies for introducing pharmacogenetics into early drug development", DRUG DISC T, 6(11), 2001, pp. 569-574

Abstract

Following the publication of the first draft of the human genome, this is a good time to re-analyse the potential contribution of genomics to drug development. Pharma, biotech and academia are already queuing up to deliver novel data impinging on every aspect of medicine and we can foresee a five-year scenario in which every new drug with a known mode of action will have a target gene sequence in the public domain. As such, current development strategies must ultimately be capable of anticipating and addressing geneticissues. This article attempts to position recent developments in genomics from an industrial perspective.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 20:07:55