Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Protective effects of lactic acid bacteria against genotoxicity in mice
Autore:
Abraham, SK; Paul, J;
Indirizzi:
Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India Jawaharlal Nehru Univ New Delhi India 110067 ci, New Delhi 110067, India
Titolo Testata:
CURRENT SCIENCE
fascicolo: 10, volume: 80, anno: 2001,
pagine: 1310 - 1312
SICI:
0011-3891(20010525)80:10<1310:PEOLAB>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MARROW CELLS; IN-VIVO; ANTIGENOTOXIC PROPERTIES; CHROMOSOME-ABERRATIONS; GASTROINTESTINAL-TRACT; INVITRO BINDING; ANTIMUTAGENS; MUTAGENS; INVIVO; CANCER;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Physical, Chemical & Earth Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Abraham, SK Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India Jawaharlal Nehru Univ New Delhi India 110067 i 110067, India
Citazione:
S.K. Abraham e J. Paul, "Protective effects of lactic acid bacteria against genotoxicity in mice", CURRENT SCI, 80(10), 2001, pp. 1310-1312

Abstract

The possible protective effects of lactic acid bacteria (LAB) against in vivo genotoxicity were assessed in mice. Culture broth containing Lactobacillus casei was orally administered to mice either Ih before intake of the genotoxins, cyclophosphamide (CPH), procarbazine (PCB) and urethane (URE) or together with PCB. In addition, an experiment was carried out in which heat-inactivated L. casei was orally administered to mice 1 h before PCB, Control animals received cell-free culture broth. Genotoxic effects were assessed in the mouse bone-marrow micronucleus test. The results suggest that pretreatment of mice with L. casei Ih before the administration of genotoxins can lead to a moderate reduction (P < 0.05) in the genotoxicity of PCB and URE, but not CPH. However, co-administration of PCB with L. casei did not show any significant effect on genotoxicity, Similarly, no significant changein genotoxicity was observed after administration of heat-inactivated LAB. From this investigation, there is limited evidence for the protective effect of LAB against in vivo genotoxicity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 10:26:44