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Titolo:
Neurophysiological signals of working memory in normal aging
Autore:
McEvoy, LK; Pellouchoud, E; Smith, ME; Gevins, A;
Indirizzi:
San Francisco Brain Res Inst, San Francisco, CA 94108 USA San Francisco Brain Res Inst San Francisco CA USA 94108 sco, CA 94108 USA SAM Technol, San Francisco, CA 94108 USA SAM Technol San Francisco CA USA94108 chnol, San Francisco, CA 94108 USA
Titolo Testata:
COGNITIVE BRAIN RESEARCH
fascicolo: 3, volume: 11, anno: 2001,
pagine: 363 - 376
SICI:
0926-6410(200106)11:3<363:NSOWMI>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
AGE-RELATED-CHANGES; EVENT-RELATED POTENTIALS; CEREBRAL BLOOD-FLOW; PATTERN-RECOGNITION METHODS; AUDITORY ODDBALL TASK; PREFRONTAL CORTEX; BRAIN POTENTIALS; VISUAL-STIMULI; FRONTAL-CORTEX; INTRACEREBRAL POTENTIALS;
Keywords:
frontal midline theta; alpha; spatial working memory; P300; electroencephalogram; event-related potential;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
108
Recensione:
Indirizzi per estratti:
Indirizzo: McEvoy, LK San Francisco Brain Res Inst, 425 Bush St,5th Floor, San Francisco, CA 94108 USA San Francisco Brain Res Inst 425 Bush St,5th Floor San Francisco CA USA 94108
Citazione:
L.K. McEvoy et al., "Neurophysiological signals of working memory in normal aging", COGN BRAIN, 11(3), 2001, pp. 363-376

Abstract

To examine how neurophysiological signals of working memory (WM) change with normal aging, we recorded EEGs from healthy groups (n = 10 each) of young (mean age = 21 years), middle-aged (mean = 47 years), and older (mean = 69 years) adults. EEGs were recorded while subjects performed easy and difficult versions of a spatial WM task. Groups were matched for IQ (mean = 123;WAIS-R) and practiced in task performance. Responses slowed with age, particularly in the more difficult task. Advanced age was associated with decreased amplitude and increased latency of the parietal P300 component of the event-related potential and an increase in the amplitude of a frontal P200 component. Spectral features of the EEG also differed between groups. Younger subjects displayed an increase in the frontal midline a rhythm with increased task difficulty, a result not observed in older subjects. Age-relatedchanges were also observed in the task-related a signal, the amplitude of which decreases as more neurons become involved in task-related processing. Young adults showed a decrease in (rv power with increased task difficultyover parietal regions but not over frontal regions. Middle-aged and older adults showed decreased a power with increased task difficulty over both frontal and parietal regions. This suggests that normal aging may be associated with changes in the fronto-parietal networks involved with spatial WM processes. Younger subjects appear to use a strategy that relies on parietal areas involved with spatial processing, whereas older subjects appear to use a strategy that relies more on frontal areas. (C) 2001 Elsevier Science B. V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 02:38:48