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Titolo:
Simulation of plasticity in the adult visual cortex
Autore:
Andrade, MA; Muro, EM; Moran, F;
Indirizzi:
Univ Complutense Madrid, Fac Quim, Dept Bioquim & Biol Mol 1, E-28040 Madrid, Spain Univ Complutense Madrid Madrid Spain E-28040 ol 1, E-28040 Madrid, Spain Inst Nacl Tecn Aeroespacial, Ctr Astrobiol, Madrid 28850, Spain Inst Nacl Tecn Aeroespacial Madrid Spain 28850 biol, Madrid 28850, Spain
Titolo Testata:
BIOLOGICAL CYBERNETICS
fascicolo: 6, volume: 84, anno: 2001,
pagine: 445 - 451
SICI:
0340-1200(200106)84:6<445:SOPITA>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
BASIC NETWORK PRINCIPLES; NEURAL ARCHITECTURE; NITRIC-OXIDE; ORIENTATION COLUMNS; OCULAR DOMINANCE; STRIATE CORTEX; EMERGENCE; MODEL; MAPS; CAT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Moran, F Univ Complutense Madrid, Fac Quim, Dept Bioquim & Biol Mol 1, E-28040 Madrid, Spain Univ Complutense Madrid Madrid Spain E-28040 8040 Madrid, Spain
Citazione:
M.A. Andrade et al., "Simulation of plasticity in the adult visual cortex", BIOL CYBERN, 84(6), 2001, pp. 445-451

Abstract

Retinal plasticity has been shown in the adult visual nervous system in mammals. Following a retinal lesion (scotoma) there is a reorganization of the cortical receptive field distribution: cortical neurons selective to visual stimuli in the area of the visual field corresponding to the retinal lesion, become selective to other parts of the visual field. In this work, we study this effect with a self-organizing neural network. In a first stage, the network reaches a pattern of connectivity that represents normal development of neuronal selectivity. The scotoma is simulated by perturbing accordingly the properties of a region of the input layer representing the retina. The system evolves to a new receptive field distribution mainly by meansof the reorganization of the intra cortical connectivity. No major change of the geniculo cortical connectivity is detected. This may explain the surprisingly short time scale of the event.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 07:25:49