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Titolo:
Effect of administration with the extract of Gymnema sylvestre R. Br leaves on lipid metabolism in rats
Autore:
Shigematsu, N; Asano, R; Shimosaka, M; Okazaki, M;
Indirizzi:
Shinshu Univ, Dept Appl Biol, Ueda, Nagano 3868567, Japan Shinshu Univ Ueda Nagano Japan 3868567 Biol, Ueda, Nagano 3868567, Japan Nihon Univ, Dept Vet Pharmacol, Coll Bioresource Sci, Fujisawa, Kanagawa 2528510, Japan Nihon Univ Fujisawa Kanagawa Japan 2528510 isawa, Kanagawa 2528510, Japan Shinshu Univ, Ctr Gene Res, Ueda, Nagano 3868567, Japan Shinshu Univ UedaNagano Japan 3868567 e Res, Ueda, Nagano 3868567, Japan
Titolo Testata:
BIOLOGICAL & PHARMACEUTICAL BULLETIN
fascicolo: 6, volume: 24, anno: 2001,
pagine: 713 - 717
SICI:
0918-6158(200106)24:6<713:EOAWTE>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLESTEROL ACYLTRANSFERASE; ACIDS; DIET; FERMENTATION; LECITHIN;
Keywords:
Gymnema sylvestre; lipid metabolism; propionic acid; cholesterol; triglyceride;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Shigematsu, N Shinshu Univ, Dept Appl Biol, 3-15-1 Tokida, Ueda, Nagano 3868567, Japan Shinshu Univ 3-15-1 Tokida Ueda Nagano Japan 3868567 , Japan
Citazione:
N. Shigematsu et al., "Effect of administration with the extract of Gymnema sylvestre R. Br leaves on lipid metabolism in rats", BIOL PHAR B, 24(6), 2001, pp. 713-717

Abstract

Extract of Gymnema sylvestre R, Br leaves (GE) was orally administered once a day to rats fed a high fat diet or normal fat diet for 3 weeks to investigate its influence on lipid metabolism, As a result, CE did not influencebody weight gain or feed intake in both diet groups during the experimental period. The apparent fat digestibility was significantly decreased by GE in both diet groups for the last 2 weeks of the experimental period, thoughnot the apparent protein digestibility, In addition, the excretion of neutral sterols and acid steroids into feces was increased by GE in both diet groups. Furthermore, GE decreased the total cholesterol and triglyceride levels in serum. On the other hand, blood lecithin-cholesterol acyltransferase(LCAT) activity was increased by GE. Moreover, it was suggested that CE influenced cecal fermentation and that propionic acid and acetic acrid contents in cecum were significantly increased by GE. Consequently, it was suggested that GE improved serum cholesterol and triglyceride levels through influence over a wide range of lipid metabolism in rats.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 15:00:13