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Titolo:
Melanoma involving the gastrointestinal tract
Autore:
Retsas, S; Christofyllakis, C;
Indirizzi:
Charing Cross Hosp, Dept Med Oncol, Melanoma Unit, London W6 8RF, England Charing Cross Hosp London England W6 8RF ma Unit, London W6 8RF, England
Titolo Testata:
ANTICANCER RESEARCH
fascicolo: 2B, volume: 21, anno: 2001,
pagine: 1503 - 1507
SICI:
0250-7005(200103/04)21:2B<1503:MITGT>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
MALIGNANT-MELANOMA; METASTATIC MELANOMA; SMALL-BOWEL; SURGICAL-TREATMENT; RESECTION; SURVIVAL;
Keywords:
chemotherapy; gastro-intestinal; melanoma; metastatic; surgery; survival;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Retsas, S Charing Cross Hosp, Dept Med Oncol, Melanoma Unit, London W6 8RF, England Charing Cross Hosp London England W6 8RF ondon W6 8RF, England
Citazione:
S. Retsas e C. Christofyllakis, "Melanoma involving the gastrointestinal tract", ANTICANC R, 21(2B), 2001, pp. 1503-1507

Abstract

We studied 19 patients, 12 males and 7 females of a median age of 49 years(range 26-76) with clinical manifestations of gastro-intestinal (GI) involvement from malignant melanoma. Their records was available from an electronic database of 2163 patients registered between 1977 and 1998 with the Melanoma Unit initially at Westminster and currently at Charing Cross Hospital. Time interval from initial presentation of melanoma to the development ofGI involvement ranged from 6 to 183 months (median 44 months). Twelve patients had a laparotomy and in eight of these resection of metastatic sites was complete. Ten patients received systemic treatment. Median survival fromGI involvement for patients who had resection of metastases was 21.5 months (range 1 to 253 months). Enterectomy, especially in the presence of solitary intestinal metastases, can palliate and may prolong survival. The role of adjuvant chemotherapy is less well defined but is worthy of consideration.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 21:21:48