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Titolo:
Efficient synthesis of chiral isoquinoline and pyrido[1,2-b]isoquinoline derivatives via intramolecular Heck reactions
Autore:
Sanchez-Sancho, F; Mann, E; Herradon, B;
Indirizzi:
CSIC, Inst Quim Organ Gen, E-28006 Madrid, Spain CSIC Madrid Spain E-28006 IC, Inst Quim Organ Gen, E-28006 Madrid, Spain
Titolo Testata:
ADVANCED SYNTHESIS & CATALYSIS
fascicolo: 4, volume: 343, anno: 2001,
pagine: 360 - 368
SICI:
1615-4150(200105)343:4<360:ESOCIA>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
PALLADIUM-MEDIATED CYCLIZATIONS; ASYMMETRIC TOTAL SYNTHESIS; SOLID-PHASE SYNTHESIS; IODO BENZYL ENAMINES; COUPLING REACTIONS; PHENYLALANINE ANALOGS; CATALYZED CYCLIZATION; ORGANIC-SYNTHESIS; SALTS; HETEROCYCLES;
Keywords:
biaryls intramolecular Heck reaction; isoquinolines; pyrido[1,2-b] isoquinolines; palladium;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
77
Recensione:
Indirizzi per estratti:
Indirizzo: Herradon, B CSIC, Inst Quim Organ Gen, Juan Cierva 3, E-28006 Madrid, Spain CSIC Juan Cierva 3 Madrid Spain E-28006 E-28006 Madrid, Spain
Citazione:
F. Sanchez-Sancho et al., "Efficient synthesis of chiral isoquinoline and pyrido[1,2-b]isoquinoline derivatives via intramolecular Heck reactions", ADV SYNTH C, 343(4), 2001, pp. 360-368

Abstract

The palladium(0)-catalyzed reaction of derivatives of gamma -amino-alpha, beta -unsaturated esters bearing an N-(2-iodobenzoyl) substituent results in an intramolecular Heck reaction, the outcome of which depends on the structure of the substrate as well as on the experimental conditions. The methodology developed has been applied to the efficient syntheses of chiral isoquinoline and pyrido[1,2-b] isoquinoline derivatives.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 07:37:08