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Titolo:
Fluid resuscitation in infantile hypertrophic pyloric stenosis
Autore:
Miozzari, HH; Tonz, M; von Vigier, RO; Bianchetti, MG;
Indirizzi:
Univ Bern, Dept Pediat Surg, CH-3012 Bern, Switzerland Univ Bern Bern Switzerland CH-3012 ediat Surg, CH-3012 Bern, Switzerland Univ Bern, Dept Pediat, CH-3012 Bern, Switzerland Univ Bern Bern Switzerland CH-3012 ept Pediat, CH-3012 Bern, Switzerland
Titolo Testata:
ACTA PAEDIATRICA
fascicolo: 5, volume: 90, anno: 2001,
pagine: 511 - 514
SICI:
0803-5253(200105)90:5<511:FRIIHP>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
METABOLIC ALKALOSIS; SERUM ELECTROLYTES; CHLORIDE; MANAGEMENT; CHILDREN; DISEASE;
Keywords:
alkalosis; dehydration; fluid therapy; hypokalaemia; pyloric stenosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Bianchetti, MG Inselspital Bern, Dept Pediat, CH-3010 Bern, Switzerland Inselspital Bern Bern Switzerland CH-3010 rn, Switzerland
Citazione:
H.H. Miozzari et al., "Fluid resuscitation in infantile hypertrophic pyloric stenosis", ACT PAEDIAT, 90(5), 2001, pp. 511-514

Abstract

The purpose of this analysis was to investigate biochemical disturbances at presentation and initial fluid resuscitation before surgery in infantile pyloric stenosis. The charts of 139 consecutive infants (113 boys and 26 girls) between 7 d and 20 wk of age with hypertrophic pyloric stenosis were reviewed. The infants were treated at the Department of Pediatric Surgery, University of Bern, Switzerland, in the period between 1987 and 1997. A trend towards hypokalaemia (13 of the 139 patients), hypochloraemia (39 patients) and especially metabolic alkalosis (98 patients) was frequently noted onadmission. In 84 patients, data on fluid management and on circulating sodium, potassium, chloride and the acid-base balance immediately before surgery were also available. In these patients a significant correlation was found between the parenteral chloride dose given for fluid repair (y = 0.310 x; r(s) = 0.54; p < 0.001) and the changes in plasma bicarbonate. The equation indicates that a chloride dose of 10 mmol/kg body weight is required to reduce plasma bicarbonate on average by 3 mmol/l. Conclusion: Since assessment bf the fluid volume stated by -physical examination and history inaccurate in infants with vomiting, the severity of metabolic alkalosis helps to define-the amount of fluid required for repair.

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Documento generato il 03/04/20 alle ore 20:27:45