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Titolo:
Endocrine disruption and human reproductive effects: An overview
Autore:
Foster, WG;
Indirizzi:
Cedars Sinai Med Ctr, Ctr Womens Hlth, Los Angeles, CA 90048 USA Cedars Sinai Med Ctr Los Angeles CA USA 90048 , Los Angeles, CA 90048 USA
Titolo Testata:
WATER QUALITY RESEARCH JOURNAL OF CANADA
fascicolo: 2, volume: 36, anno: 2001,
pagine: 253 - 271
SICI:
1201-3080(2001)36:2<253:EDAHRE>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEPRESSED SEMEN QUALITY; EPIDERMAL GROWTH-FACTOR; PAST 20 YEARS; SEX-RATIO; TESTICULAR CANCER; ESTROGEN-RECEPTOR; SPERM COUNTS; 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN TCDD; LACTATIONAL EXPOSURE; SUBCHRONIC EXPOSURE;
Keywords:
endocrine disruptors; reproduction; development; semen quality; endometriosis;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
108
Recensione:
Indirizzi per estratti:
Indirizzo: Foster, WG Cedars Sinai Med Ctr, Ctr Womens Hlth, Los Angeles, CA 90048 USA Cedars Sinai Med Ctr Los Angeles CA USA 90048 es, CA 90048 USA
Citazione:
W.G. Foster, "Endocrine disruption and human reproductive effects: An overview", WAT QUAL RE, 36(2), 2001, pp. 253-271

Abstract

Humans of all ages interact with their environment on a daily basis and are thus exposed to a variety of both man-made and naturally occurring chemicals through the air they breath, the water they drink and the food they eat. The potential for exposure to environmental contaminants to impact the function of the reproductive system and affect normal development of the reproductive tract has become an area of increasing concern at all levels of society. Environment Canada and Health Canada jointly organized a workshop toreview the current state of knowledge on endocrine disrupting compounds (EDCs) and to establish a national science agenda on the scientific assessment of EDCs. This report summarizes the key scientific literature pertaining to the role of EDCs in a number of selected human reproductive/developmental outcomes. Change in the frequency of health outcome trends, epidemiological evidence of an association between the health outcome of concern and exposure to EDCs, and mechanistic evidence of receptor-mediated effects were the criteria used to evaluate the strength of the evidence. While it cannot be concluded that EDCs cause reproductive effects in the general Canadian population, the weight of evidence provides cause for continued concern.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 11:48:13