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Titolo:
Discrimination of small hepatic hemangiomas from hypervascular malignant tumors smaller than 3 cm with three-phase helical CT
Autore:
Kim, T; Federle, MP; Baron, RL; Peterson, MS; Kawamori, Y;
Indirizzi:
Univ Pittsburgh, Sch Med, Dept Radiol, Div Abdominal Imaging, Pittsburgh, PA 15213 USA Univ Pittsburgh Pittsburgh PA USA 15213 Imaging, Pittsburgh, PA 15213 USA
Titolo Testata:
RADIOLOGY
fascicolo: 3, volume: 219, anno: 2001,
pagine: 699 - 706
SICI:
0033-8419(200106)219:3<699:DOSHHF>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONTRAST-ENHANCED CT; DYNAMIC BOLUS CT; HEPATOCELLULAR-CARCINOMA; ARTERIAL PHASE; DIFFERENTIAL-DIAGNOSIS; CAVERNOUS HEMANGIOMAS; LIVER-LESIONS; 2-PHASE CT; SPIRAL CT; METASTASES;
Keywords:
angioma; liver, CT; liver neoplasms; neoplasms, metastases;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Federle, MP Univ Pittsburgh, Sch Med, Dept Radiol, Div Abdominal Imaging, 200 Lothrop St, Pittsburgh, PA 15213 USA Univ Pittsburgh 200 Lothrop St Pittsburgh PA USA 15213 213 USA
Citazione:
T. Kim et al., "Discrimination of small hepatic hemangiomas from hypervascular malignant tumors smaller than 3 cm with three-phase helical CT", RADIOLOGY, 219(3), 2001, pp. 699-706

Abstract

PURPOSE: To compare the appearance of small hepatic hemangiomas at nonenhanced acid contrast material-enhanced helical computed tomography (CT) with that of small (<3-cm) hypervascular malignant liver tumors and to evaluate the accuracy of multiphase helical CT for differentiating small hemangiomasfrom small hypervascular malignant tumors. MATERIALS AND METHODS: Radiologists reviewed multiphase helical CT liver images in 86 patients with 37 hemangiomas and 49 malignant liver tumors. They evaluated lesion type and degree of enhancement for change from arterial to portal venous phase. They rated their confidence in the discrimination of hemangiomas from malignant tumors. RESULTS: At arterial phase CT, enhancement similar to aortic enhancement was observed in 19%-32% of hemangiomas and 0%-2% of malignant tumors; globular enhancement, in 62%-68% and 4%-12%, respectively. At portal venous phaseCT, enhancement similar to blood pool enhancement was observed ih 43%-54% of hemangiomas and 4%-14% of malignant tumors; globular enhancement, in 46%-49% and 0%-2%, respectively. For all readers and all phases of enhancement, the area under the receiver operating characteristic curves was 0.81-0.87, indicating that inherent accuracy of CT is high and that there was no significant difference (P > .28) in overall accuracy. Readers diagnosed hemangiomas with 47%-53% mean sensitivity with all enhancement phases and diagnosed malignant lesions with 95% mean specificity. CONCLUSION: Small hemangiomas frequently show atypical appearances at CT. Two-phase helical CT does not improve sensitivity but does improve specificity for differentiating hemangiomas from hypervascular malignant tumors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 16:04:06