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Titolo:
Cerebral infarction in chronic meningitis: a comparison of tuberculous meningitis and cryptococcal meningitis
Autore:
Lan, SH; Chang, WN; Lu, CH; Lui, CC; Chang, HW;
Indirizzi:
Chang Gung Mem Hosp, Dept Neurol, Kaohsiung, Taiwan Chang Gung Mem Hosp Kaohsiung Taiwan sp, Dept Neurol, Kaohsiung, Taiwan Chang Gung Mem Hosp, Dept Radiol, Kaohsiung, Taiwan Chang Gung Mem Hosp Kaohsiung Taiwan sp, Dept Radiol, Kaohsiung, Taiwan Natl Sun Yat Sen Univ, Dept Biol Sci, Kaohsiung, Taiwan Natl Sun Yat Sen Univ Kaohsiung Taiwan Dept Biol Sci, Kaohsiung, Taiwan
Titolo Testata:
QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS
fascicolo: 5, volume: 94, anno: 2001,
pagine: 247 - 253
SICI:
1460-2725(200105)94:5<247:CIICMA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACQUIRED-IMMUNODEFICIENCY-SYNDROME; CENTRAL-NERVOUS-SYSTEM; MYCOBACTERIUM-TUBERCULOSIS; PROGNOSTIC FACTORS; DRUG-RESISTANCE; HYDROCEPHALUS; TAIWAN; ADULTS; SHUNT; NEOFORMANS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Lu, CH Chang Gung Mem Hosp, Dept Neurol, 123 Ta Pei Rd, Kaohsiung, Taiwan Chang Gung Mem Hosp 123 Ta Pei Rd Kaohsiung Taiwan hsiung, Taiwan
Citazione:
S.H. Lan et al., "Cerebral infarction in chronic meningitis: a comparison of tuberculous meningitis and cryptococcal meningitis", QJM-MON J A, 94(5), 2001, pp. 247-253

Abstract

Twenty-eight patients with cerebral infarction secondary to chronic meningitis were retrospectively identified at our institution over a period of 5 years. They accounted for 47% (17/36) of tuberculous meningitis (TBM) and 32% (11/34) of cryptococcal meningitis cases. Single infarctions were found in 15 patients and multiple infarctions in 13. The distribution of single infarctions was: basal ganglia 7; internal capsule 3; thalamus 1; cerebellum1; and cortical infarct 3. Therapeutic outcomes at 3 months were determined using a modified Barthel Index. At follow-up of 3 months or more, 10 had good outcomes while the other 18 had poor outcomes. The 18 with poor outcomes included six who died, and 12 who had severe neurological sequelae, TBM and cryptococcal meningitis shared similar clinical features, both being frequently associated with other neurological complications, including hydrocephalus, cranial nerve palsy, and seizures in our patients. However, extracranial involvement, such as spinal and pulmonary involvement, was more commonly found in TBM patients. Cerebral infarction can occur in both the acutestage and later stages of treatment. Mortality and morbidity are high, andearly diagnosis and appropriate antimicrobial treatment are essential. If hydrocephalus is demonstrated, early ventricular decompression is needed toprevent further cerebral ischaemia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 06:31:46