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Titolo:
Immunohistochemical aspects of basal cell adenoma and canalicular adenoma of salivary glands
Autore:
de Sousa, SOM; de Araujo, NS; Correa, L; Soubhia, AMP; de Araujo, VC;
Indirizzi:
Univ Sao Paulo, Dept Oral Pathol, Sch Dent, BR-05508900 Sao Paulo, Brazil Univ Sao Paulo Sao Paulo Brazil BR-05508900 BC05508900 Sao Paulo, Brazil Univ Sao Paulo Aracatuba, Dept Oral Pathol, Sch Dent, Aracatuba, SP, Brazil Univ Sao Paulo Aracatuba Aracatuba SP Brazil Dent, Aracatuba, SP, Brazil
Titolo Testata:
ORAL ONCOLOGY
fascicolo: 4, volume: 37, anno: 2001,
pagine: 365 - 368
SICI:
1368-8375(200106)37:4<365:IAOBCA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
MONOMORPHIC-ADENOMA; ULTRASTRUCTURE;
Keywords:
basal cell adenoma; canalicular adenoma; salivary gland tumours; immunohistochemistry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: de Sousa, SOM Univ Sao Paulo, Dept Oral Pathol, Sch Dent, Av Prof Lineu Prestes 2227, BR-05508900 Sao Paulo, Brazil Univ Sao Paulo Av Prof Lineu Prestes 2227 Sao Paulo Brazil BR-05508900 BC
Citazione:
S.O.M. de Sousa et al., "Immunohistochemical aspects of basal cell adenoma and canalicular adenoma of salivary glands", ORAL ONCOL, 37(4), 2001, pp. 365-368

Abstract

Basal cell adenoma is a benign epithelial neoplasm with a uniform histologic appearance dominated by basaloid cells. Those cells may be distributed in various arrangements as solid, trabecular, tubular and membranous. Canalicular adenoma is also a benign neoplasm composed by columnar cells arrangedin branching and interconnecting cords of single or double cell thick rows. Then is some disagreement among investigators about whether canalicular adenoma should be included within the basal cell adenoma histologic spectrum. In the present study we compared the expression of cytokeratins (CK), vimentin and muscle-specific actin, utilizing immunohistochemical technique, in three cases diagnosed as basal cell adenomas predominantly of the solid type, and three cases of canalicular adenomas. The results obtained showed adistinct immunoprofile for both neoplasms. Solid areas of basal cell adenomas did not stain for any of the tested antibodies; only when there was tubular differentiation, those structures expressed CKs 7, 8, 14, and 19 in luminal cells and vimentin in non-luminal cells. On the other hand, canalicular adenomas strongly expressed CKs 7 and 13. The panel of antibodies utilized supports the separation of the two entities. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 15:10:57