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Titolo:
Perfusion imaging using dynamic arterial spin labeling (DASL)
Autore:
Barbier, EL; Silva, AC; Kim, SG; Koretsky, AP;
Indirizzi:
NINDS, LFMI, NIH, Bethesda, MD 20892 USA NINDS Bethesda MD USA 20892NINDS, LFMI, NIH, Bethesda, MD 20892 USA NINDS, MRI Res Facil, NIH, Bethesda, MD 20892 USA NINDS Bethesda MD USA 20892 S, MRI Res Facil, NIH, Bethesda, MD 20892 USA Univ Minnesota, Sch Med, Dept Radiol, Ctr Magnet Resonance Res, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 ce Res, Minneapolis, MN 55455 USA
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 6, volume: 45, anno: 2001,
pagine: 1021 - 1029
SICI:
0740-3194(200106)45:6<1021:PIUDAS>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; CONTROLLED CORTICAL IMPACT; MAGNETIZATION-TRANSFER; ISOFLURANE ANESTHESIA; RAT-BRAIN; WATER; TIME; VOLUME; HALOTHANE; INVERSION;
Keywords:
cerebral blood flow; cerebral blood volume; MR; frequency filtering; transit time;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Koretsky, AP NINDS, LFMI, NIH, Room 10-B1D118,MSC 1065, Bethesda, MD 20892USA NINDS Room 10-B1D118,MSC 1065 Bethesda MD USA 20892 20892 USA
Citazione:
E.L. Barbier et al., "Perfusion imaging using dynamic arterial spin labeling (DASL)", MAGN RES M, 45(6), 2001, pp. 1021-1029

Abstract

Recently, a technique based on arterial spin labeling, called dynamic arterial spin labeling (DASL (Magn Reson Med 1999;41:299-308)), has been introduced to measure simultaneously the transit time of the labeled blood from the labeling plane to the exchange site, the longitudinal relaxation time ofthe tissue, and the perfusion of the tissue. This technique relies on the measurement of the tissue magnetization response to a time varying labelingfunction. The analysis of the characteristics of the tissue magnetization response (transit time, filling time constant, and perfusion) allows for quantification of the tissue perfusion and for transit time map computations. In the present work, the DASL scheme is used in conjuction with echo planar imaging at 4.7 T to produce brain maps of perfusion and transit time in the anesthetized rat, under graded hypercapnia. The data obtained show the variation of perfusion and transit time as a function of arterial pCO(2), Based on the data, CO2 reactivity maps are computed. Published 2001 Wiley-Liss, Inc.(dagger).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 14:43:31