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Titolo:
The potencial role of rare earths in the pathogenesis of interstitial lungdisease: a case report of movie projectionist as investigated by neutron activation analysis
Autore:
Porru, S; Placidi, D; Quarta, C; Sabbioni, E; Pietra, R; Fortaner, S;
Indirizzi:
European Commiss, Joint Res Ctr, Inst Environm, Life Sci Unit, I-21020 Ispra, Va, Italy European Commiss Ispra Va Italy I-21020 ci Unit, I-21020 Ispra, Va, Italy Univ Brescia, Inst Occupat Hlth, I-25125 Brescia, Italy Univ Brescia Brescia Italy I-25125 Occupat Hlth, I-25125 Brescia, Italy Hosp Gardone Val Trompia, I-25063 Brescia, Italy Hosp Gardone Val TrompiaBrescia Italy I-25063 a, I-25063 Brescia, Italy
Titolo Testata:
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
fascicolo: 4, volume: 14, anno: 2001,
pagine: 232 - 236
SICI:
0946-672X(200104)14:4<232:TPRORE>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
PNEUMOCONIOSIS; CERIUM;
Keywords:
cerium; rare earths; occupational exposure; interstitial lung fibrosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Sabbioni, E European Commiss, Joint Res Ctr, Inst Environm, Life Sci Unit,I-21020 Ispra, Va, Italy European Commiss Ispra Va Italy I-21020 1020 Ispra, Va, Italy
Citazione:
S. Porru et al., "The potencial role of rare earths in the pathogenesis of interstitial lungdisease: a case report of movie projectionist as investigated by neutron activation analysis", J TR ELEM M, 14(4), 2001, pp. 232-236

Abstract

A 60-year-old male subject who worked as a movie projectionist and who wasexposed for 12 years to rare earths (RE) containing dusts from cored are light carbon electrodes was investigated. Chest X-ray films and pulmonary function tests showed an interstitial lung disease, emphysema and a severe obstructive impairment with marked decrease of carbon monoxide diffusion capacity. The histological examination of a transbronchial biopsy confirmed thediffuse interstitial lung fibrosis. Neutron activation analysis (NAA) of the biopsy showed concentrations of cerium (Ce), lanthanum (La), neodimium (Nd), samarium (Sm), terbium (Tb) and ytterbium (Yb) which were high compared to the corresponding elements in the transbronchial biopsies of 5 unexposed subjects as a control group. Thorium (Th) (which is generally present asan impurity of the RE compounds) was also determined in order to estimate the radiation dose in the lung of the worker. On the basis of the clinical observations, of the analytical results by neutron activation analysis of RE and of the presence of Th in the transbronchial biopsy, as well as of the differential diagnosis, which tended to exclude other occupational or non-occupational lung diseases, a relation between the observed interstitial lung fibrosis and occupational exposure to RE is highly probable.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 00:11:42