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Titolo:
The effects of slice-selective excitation/refocusing in localized spectralediting with gradient-selected double-quantum coherence transfer
Autore:
Lei, H; Dunn, J;
Indirizzi:
Dartmouth Med Sch, Dept Diagnost Radiol, Hanover, NH 03755 USA Dartmouth Med Sch Hanover NH USA 03755 nost Radiol, Hanover, NH 03755 USA
Titolo Testata:
JOURNAL OF MAGNETIC RESONANCE
fascicolo: 1, volume: 150, anno: 2001,
pagine: 17 - 25
SICI:
1090-7807(200105)150:1<17:TEOSEI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-VIVO DETECTION; NMR-SPECTROSCOPY; HUMAN BRAIN; LACTATE; FILTER; INVIVO; PULSES; SEQUENCE; SYSTEMS; TUMORS;
Keywords:
spectral editing; double-quantum coherence transfer; double-quantum filtering; chemical shift displacement artifact; spatial localization;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Lei, H Dartmouth Med Sch, Dept Diagnost Radiol, HB 7786,Vail 709, Hanover,NH 03755 USA Dartmouth Med Sch HB 7786,Vail 709 Hanover NH USA 03755 H 03755 USA
Citazione:
H. Lei e J. Dunn, "The effects of slice-selective excitation/refocusing in localized spectralediting with gradient-selected double-quantum coherence transfer", J MAGN RES, 150(1), 2001, pp. 17-25

Abstract

Spectral editing using gradient-selected double-quantum filtering (DQF) with PRESS localization has been used for selective observation of metabolites in vivo. In previous studies using localized DQF sequences, it is generally assumed that the slice-selective pulses used in the sequence have no roles in coherence transfer, and do not interfere with DQE. To validate this assumption, the effects of slice-selective excitation/refocusing on DQF wereinvestigated in DQF lactate editing sequences combined with PRESS localization. Contrary to the previous assumption, the results show that, due to chemical shift displacement artifact and J coupling, slice selection in DQF does interfere with coherence transfer, affecting both the accuracy of spatial localization and the detection sensitivity adversely. In the case of lactate editing, the effects of this interference can be accounted for simply by adjusting the strength of the slice-selection gradients and by using narrowband slice-selective refocusing pulses. (C) 2001 Academic Press.

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Documento generato il 02/04/20 alle ore 00:21:47