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Titolo: Borna disease virus - does it infect humans and cause psychiatric disorders?
Autore: Lieb, K; Staeheli, P;
- Indirizzi:
- Univ Freiburg, Dept Virol, D-79104 Freiburg, Germany Univ Freiburg Freiburg Germany D-79104 Virol, D-79104 Freiburg, Germany Univ Freiburg, Dept Psychiat & Psychotherapy, D-79104 Freiburg, Germany Univ Freiburg Freiburg Germany D-79104 herapy, D-79104 Freiburg, Germany
- Titolo Testata:
- JOURNAL OF CLINICAL VIROLOGY
fascicolo: 2,
volume: 21,
anno: 2001,
pagine: 119 - 127
- SICI:
- 1386-6532(200105)21:2<119:BDV-DI>2.0.ZU;2-U
- Fonte:
- ISI
- Lingua:
- ENG
- Soggetto:
- BLOOD MONONUCLEAR-CELLS; CHRONIC-FATIGUE-SYNDROME; MENTAL-HEALTH WORKERS; HUMAN BRAIN-TISSUE; NUCLEIC-ACID; NEUROPSYCHIATRIC DISORDERS; SCHIZOPHRENIC-PATIENTS; HIGH SEROPREVALENCE; JAPANESE PATIENTS; MOOD DISORDERS;
- Keywords:
- Borna disease virus; antibodies; RT-PCR; psychiatric disorders;
- Tipo documento:
- Article
- Natura:
- Periodico
- Settore Disciplinare:
- Clinical Medicine
- Citazioni:
- 58
- Recensione:
- Indirizzi per estratti:
- Indirizzo: Staeheli, P Univ Freiburg, Dept Virol, Hauptstr 5 11, D-79104 Freiburg, Germany Univ Freiburg Hauptstr 5 11 Freiburg Germany D-79104 Germany
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- Citazione:
- K. Lieb e P. Staeheli, "Borna disease virus - does it infect humans and cause psychiatric disorders?", J CLIN VIRO, 21(2), 2001, pp. 119-127
Abstract
Antibodies recognizing Borna disease virus (BDV) antigens were first demonstrated in the blood of psychiatric patients approximate to 15 years ago. Since that time, a highly controversial debate arose whether BDV infects humans and whether it causes psychiatric disorders. In this review, we critically discuss the results of numerous studies that assessed this possibility by using virological and serological methods. We conclude that there is presently no strong experimental evidence supporting the notion that BDV is a human pathogen. The possibility remains, however, that an antigenically related agent is associated with human psychiatric disorders. (C) 2001 Elsevier Science B.V. All rights reserved.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 02:11:39