Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
In vivo and in vitro techniques to determine the biological activity of food allergens
Autore:
Poulsen, LK;
Indirizzi:
Natl Univ Hosp, Allergy Unit, Lab Med Allergol, FIN 7542, DK-2200 Kobenhavn N, Denmark Natl Univ Hosp Kobenhavn Denmark N IN 7542, DK-2200 Kobenhavn N, Denmark
Titolo Testata:
JOURNAL OF CHROMATOGRAPHY B
fascicolo: 1-2, volume: 756, anno: 2001,
pagine: 41 - 55
SICI:
1387-2273(20010525)756:1-2<41:IVAIVT>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEGUME BOTANICAL FAMILY; SKIN PRICK TEST; HISTAMINE-RELEASE; DOUBLE-BLIND; MILK ALLERGY; CROSS-ALLERGENICITY; ASTHMATIC-CHILDREN; CODFISH ALLERGY; BIRCH POLLEN; CELL-LINE;
Keywords:
reviews; food allergy; double-blind placebo-controlled food challenge; skin prick test; basophil histamine release; immunoglobins;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
64
Recensione:
Indirizzi per estratti:
Indirizzo: Poulsen, LK Blegdamsvej 9, DK-2100 Kobenhavn O, Denmark Blegdamsvej 9 Kobenhavn Denmark O -2100 Kobenhavn O, Denmark
Citazione:
L.K. Poulsen, "In vivo and in vitro techniques to determine the biological activity of food allergens", J CHROMAT B, 756(1-2), 2001, pp. 41-55

Abstract

Methods for determination of the biological activity of food allergens comprise both determination of the allergenic potency, i.e. the capability to elicit an allergic reaction in an already sensitized individual, and the allergenic potential, i.e. the risk for sensitizing a hitherto non-allergic individual. Several methods are discussed for determination of potency including the double-blinded placebo-controlled food challenge, skin testing, invitro effector cell assays such as basophil histamine release, and IgE-based techniques such as RAST and RAST inhibition. No reliable methods have yet been developed which can predict the allergenic potential of a food or a Food allergen. The progress in the areas of stability studies and animal models for food allergy are discussed. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 22:09:11