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Titolo:
Hormones, weight change and menopause
Autore:
Davies, KM; Heaney, RP; Recker, RR; Barger-Lux, MJ; Lappe, JM;
Indirizzi:
Creighton Univ, Osteoporosis Res Ctr, Omaha, NE 68131 USA Creighton Univ Omaha NE USA 68131 teoporosis Res Ctr, Omaha, NE 68131 USA
Titolo Testata:
INTERNATIONAL JOURNAL OF OBESITY
fascicolo: 6, volume: 25, anno: 2001,
pagine: 874 - 879
SICI:
0307-0565(200106)25:6<874:HWCAM>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
BODY-FAT DISTRIBUTION; REPLACEMENT THERAPY; BLOOD-PRESSURE; WOMEN; AGE; TRANSITION; DISEASE; HEALTH; RISK;
Keywords:
menopause; estrogen; weight gain; hormone replacement therapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Heaney, RP Creighton Univ, Osteoporosis Res Ctr, 601 N 30th St,Suite 4841,Omaha, NE 68131 USA Creighton Univ 601 N 30th St,Suite 4841 Omaha NE USA 68131 USA
Citazione:
K.M. Davies et al., "Hormones, weight change and menopause", INT J OBES, 25(6), 2001, pp. 874-879

Abstract

OBJECTIVE: To determine total body weight change occurring in women at mid-life, specifically with respect to occurrence of menopause and use of estrogen. DESIGN: Retrospective analysis of body weight measurements accumulated in two cohorts of healthy women participating in studies of skeletal metabolism. SUBJECTS: Cohort 1: 191 healthy nuns enrolled in a prospective study of osteoporosis risk, aged 35 - 45 in 1967; cohort 2: 75 women aged 46 or older and still menstruating, enrolled in 1988 in a study of bone cell dynamics across menopause. Roughly one-third of each group received hormone replacement after menopause. MEASUREMENTS: Body weight and height, age, menstrual status and use of estrogen replacement. Cohort 1: 608 measurements at 5y intervals spanning a period from 17y before to 22y after menopause; cohort 2. 1180 measurements at6-month intervals spanning a period from 5y prior to 5y after menopause. RESULTS: In cohort 1 weight rose as a linear function of age (both chronological and menopausal), both before and after cessation of ovarian function, at a rate of similar to0.43%y(-1). Neither the menopausal transition nor the use of estrogen had an appreciable effect on this rate of gain. In cohort 2 the rate of gain seemed to diminish slightly at menopause. As with cohort 1, hormone replacement (or its absence) had no appreciable effect on weight. CONCLUSIONS: The long-term, total body weight trajectory at mid-life is not influenced appreciably by either cessation of ovarian function or by hormone replacement.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 16:13:03