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Titolo:
Depressive symptoms among cognitively normal versus cognitively impaired elderly subjects
Autore:
Li, YS; Meyer, JS; Thornby, J;
Indirizzi:
VAMC, Cerebrovasc Res Labs, Houston, TX 77030 USA VAMC Houston TX USA 77030 MC, Cerebrovasc Res Labs, Houston, TX 77030 USA Baylor Coll Med, Vet Adm Med Ctr, Biostat Lab, Dept Neurol, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 , Dept Neurol, Houston, TX 77030 USA
Titolo Testata:
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
fascicolo: 5, volume: 16, anno: 2001,
pagine: 455 - 461
SICI:
0885-6230(200105)16:5<455:DSACNV>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTI-INFARCT DEMENTIA; ALZHEIMERS-DISEASE; VASCULAR DEMENTIA; MAJOR DEPRESSION; RISK-FACTORS; GERIATRIC DEPRESSION; POPULATION; PREVALENCE; PROGRESSION; DISABILITY;
Keywords:
dementia; depressive symptoms; prevalence; risk factors;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Meyer, JS VAMC, Cerebrovasc Res Labs, Bldg 110,Room 225,2002 Holcombe Blvd151A, Houston, TX 77030 USA VAMC Bldg 110,Room 225,2002 Holcombe Blvd 151AHouston TX USA 77030
Citazione:
Y.S. Li et al., "Depressive symptoms among cognitively normal versus cognitively impaired elderly subjects", INT J GER P, 16(5), 2001, pp. 455-461

Abstract

Objectives The present cross-sectional study analyzed the prevalence and severity of depressive symptoms among patients with Alzheimer's disease (DAT), vascular dementia (VAD), and among the cognitively normal elderly. Putative risk factors contributing to depression were likewise evaluated. Methods Seventy-six DAT patients, 51 VAD patients, and 121 cognitively normal subjects were admitted to the study. Questionnaires concerning demography and their vascular and familial risk factors together with results of neuropsychological testing by combined Mini-Mental Status Examinations (MMSE), Cognitive Capacity Screening Examinations (CCSE), and Hamilton DepressionRating Scales (HDRS) were obtained so what resulting data would be statistically analyzed. Results Prevalence of depressive symptoms among VAD, DAT, and cognitively normal elderly were 31.4%, 19.9%, and 13.2%, respectively. 25.5% of VAD and13.2% of DAT patients had depression of mild to moderate degrees. Regression analysis revealed that diagnosis of VAD and DAT, heart disease, and pasthistory of depression was significantly associated with high HDRS scores. There was no correlation between degree of depression and severity of cognitive impairments. Conclusion Mild to moderate depression is a common comorbidity with organic dementia, especially VAD, but associated depression is independent of severity of cognitive impairments. Copyright (C) 2001 John Wiley & Sons, Ltd.

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Documento generato il 01/04/20 alle ore 17:54:16