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Titolo:
Heterogeneity of hepatic parenchymal enhancement on computed tomography during arterial portography: quantitative analysis of correlation with severity of hepatic fibrosis
Autore:
Taura, T; Nakamura, K; Takashima, S; Kaminou, T; Yamada, R; Shuto, T; Wakasa, K;
Indirizzi:
Ashihara Hosp, Dept Radiol, Naniwa Ku, Osaka 5560025, Japan Ashihara HospOsaka Japan 5560025 adiol, Naniwa Ku, Osaka 5560025, Japan Osaka City Univ Sch, Dept Radiol, Abeno Ku, Osaka 5458585, Japan Osaka City Univ Sch Osaka Japan 5458585 , Abeno Ku, Osaka 5458585, Japan Osaka City Univ Sch, Dept Surg 2, Abeno Ku, Osaka 5458585, Japan Osaka City Univ Sch Osaka Japan 5458585 , Abeno Ku, Osaka 5458585, Japan Osaka City Univ Sch, Dept Pathol, Abeno Ku, Osaka 5458585, Japan Osaka City Univ Sch Osaka Japan 5458585 , Abeno Ku, Osaka 5458585, Japan
Titolo Testata:
HEPATOLOGY RESEARCH
fascicolo: 2, volume: 20, anno: 2001,
pagine: 182 - 192
SICI:
1386-6346(200106)20:2<182:HOHPEO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLASSIFICATION; CIRRHOSIS;
Keywords:
computed tomography during arterial portography; hepatic parenchyma; heterogeneity of enhancement; histopathology; liver cirrhosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Taura, T Ashihara Hosp, Dept Radiol, Naniwa Ku, 2-13-19 Naniwahigashi, Osaka 5560025, Japan Ashihara Hosp 2-13-19 Naniwahigashi Osaka Japan 5560025 5, Japan
Citazione:
T. Taura et al., "Heterogeneity of hepatic parenchymal enhancement on computed tomography during arterial portography: quantitative analysis of correlation with severity of hepatic fibrosis", HEPATOL RES, 20(2), 2001, pp. 182-192

Abstract

Background/Aims: In patients with chronic liver disease, heterogeneous enhancement of liver parenchyma is often noted on computed tomography during arterial portography (CTAP). We investigated the factors contributing to theheterogeneous enhancement and its relationship with postoperative histopathological findings. Methodology: Eighty-seven patients who had undergone a right lobectomy for liver tumor after CTAP were evaluated. The heterogeneity of hepatic parenchymal enhancement on CTAP was assessed quantitatively using standard deviation of mean CT numbers for five ROIs (S.D.) set in the right hepatic lobe, and comparatively evaluated among three histological groups (liver cirrhosis (LC, n =41), chronic hepatitis (CH, n = 33), and normal liver (Normal, n = 13)). Severity of fibrosis and degree of splenomegaly (Sp) were taken up as factors contributory to the heterogeneity, and were assessed for correlation with the S.D. Results: The range (mean) of S.D. wasLC, 3.07-17.64 (9.10); CH, 1.83-11.12 (6.77); and Normal, 2.06-8.89 (5.64)(Scheffe's F-test: LC vs CH, P < 0.0005; LC vs Normal, P < 0.0002). The higher fibrosis group exhibited significantly greater S.D. values as comparedwith the lower fibrosis group (Scheffe's F-test: P < 0.00003). Coefficientof correlation between the S.D. and the Sp was 0.295 (P < 0.005). Conclusion: There was a fair possibility of LC in patients with heterogeneous enhancement of liver parenchyma on CTAP. The severity of liver fibrosis and the degree of splenomegaly were considered to be factors contributing to the heterogeneous enhancement. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 02:10:09