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Titolo:
Mobilisation of trehalose in mutants of the cyclic AMP signalling pathway,cr-1 (CRISP-1) and mcb (microcycle conidiation), of Neurospora crassa
Autore:
de Pinho, CA; de Lourdes, M; Polizeli, TM; Jorge, JA; Terenzi, HF;
Indirizzi:
Univ Sao Paulo, Dept Biol, Fac Filosofia Ciencias & Letras Ribeirao Preto,BR-14040901 Ribeirao Preto, Brazil Univ Sao Paulo Ribeirao Preto Brazil BR-14040901 BCibeirao Preto, Brazil
Titolo Testata:
FEMS MICROBIOLOGY LETTERS
fascicolo: 1, volume: 199, anno: 2001,
pagine: 85 - 89
SICI:
0378-1097(20010515)199:1<85:MOTIMO>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEPENDENT PROTEIN-KINASE; SACCHAROMYCES-CEREVISIAE; ADENYLATE-CYCLASE; ASPERGILLUS-NIDULANS; HEAT-SHOCK; YEAST; FUNGI; TREHALASES; GLYCOGEN; THERMOTOLERANCE;
Keywords:
trehalose; cyclic AMP; trehalase; cr-1 mutant; mcb mutant; Neurospora crassa;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Terenzi, HF Univ Sao Paulo, Dept Biol, Fac Filosofia Ciencias & Letras Ribeirao Preto,Av Bandeirantes 3900, BR-14040901 Ribeirao Preto, Brazil Univ Sao Paulo Av Bandeirantes 3900 Ribeirao Preto Brazil BR-14040901 BC
Citazione:
C.A. de Pinho et al., "Mobilisation of trehalose in mutants of the cyclic AMP signalling pathway,cr-1 (CRISP-1) and mcb (microcycle conidiation), of Neurospora crassa", FEMS MICROB, 199(1), 2001, pp. 85-89

Abstract

The influence of the cAMP-signalling pathway on the metabolism of trehalose in Neurospora crassa was investigated. The changes in intracellular trehalose concentration were measured in two mutants affected in components of the cAMP-signalling pathway. tr-l (crisp-l), deficient in adenylyl cyclase activity, and, mch (microcyclic conidiation), deficient in the regulatory subunit of PKA. Rapid mobilisation of intracellular trehalose in the wild-type occurred, either at the onset of germination, or after a heat shock, and by carbon starvation. Mutant cr-I failed to mobilise trehalose at germination, but behaved almost normally after a heat shock, or during carbon starvation. On the other hand, the levels of trehalose in mcb fell to values muchlower than in the wild-type at germination, but accumulated trehalose normally during a heat shock. These results are consistent with the involvementof cAMP in the activation of the neutral trehalase at the onset of germination. However, the control of the enzyme under the other physiological conditions which also promote mobilisation of intracellular trehalose was apparently independent of cAMP-signalling. (C) 2001 Published by Elsevier Science B.V. on behalf of the Federation of European Microbiological Societies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 00:41:28