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Titolo:
Selected features of nonendocrine pancreatic cancer
Autore:
Anderson, KM; Harris, JE;
Indirizzi:
Rush Med Coll, Dept Med, Sect Med Oncol, Chicago, IL 60612 USA Rush Med Coll Chicago IL USA 60612 Sect Med Oncol, Chicago, IL 60612 USA Rush Med Coll, Dept Biochem, Chicago, IL 60612 USA Rush Med Coll Chicago IL USA 60612 l, Dept Biochem, Chicago, IL 60612 USA
Titolo Testata:
EXPERIMENTAL BIOLOGY AND MEDICINE
fascicolo: 6, volume: 226, anno: 2001,
pagine: 521 - 537
SICI:
1535-3702(200106)226:6<521:SFONPC>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROGRAMMED CELL-DEATH; TUMOR-SUPPRESSOR GENE; RADICAL SPIN TRAP; NF-KAPPA-B; GROWTH-FACTOR; INDUCED APOPTOSIS; POOR-PROGNOSIS; CLINICAL-SIGNIFICANCE; SIGNAL-TRANSDUCTION; TELOMERASE ACTIVITY;
Keywords:
topics in non-endocrine pancreatic cancer;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
190
Recensione:
Indirizzi per estratti:
Indirizzo: Anderson, KM Rush Med Coll, Dept Med, Sect Med Oncol, Chicago, IL 60612 USA Rush Med Coll Chicago IL USA 60612 ol, Chicago, IL 60612 USA
Citazione:
K.M. Anderson e J.E. Harris, "Selected features of nonendocrine pancreatic cancer", EXP BIOL ME, 226(6), 2001, pp. 521-537

Abstract

We survey some interesting features of gene expression in nonendocrine pancreatic cancer, the response to some less widely known agents as they impact an pancreatic cell proliferation and programmed death, and several developing approaches to therapy. The proliferative and cellular suicide responses of Panc-1 cells to the free radical spin trap, NTBN, and to the 5-lipoxygenease inhibitor, MK 886, the latter assessed with CLONTECH Atlas Human cDNA Array 1, are reviewed. Difficulties in identifying those factors whose suppression or augmentation could result in inhibition of malignantly transformed cell properties are considered.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:34:25