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Titolo:
Inhaled corticosteroid therapy reduces the risk of rehospitalization and all-cause mortality in elderly asthmatics
Autore:
Sin, DD; Tu, JV;
Indirizzi:
Univ Alberta, Walter C Mackenzie Ctr 2E4 29, Dept Med, Edmonton, AB, Canada Univ Alberta Edmonton AB Canada r 2E4 29, Dept Med, Edmonton, AB, Canada Univ Toronto, Sunnybrook & Womens Coll, Hlth Sci Ctr, ICES, Toronto, ON, Canada Univ Toronto Toronto ON Canada , Hlth Sci Ctr, ICES, Toronto, ON, Canada Univ Toronto, Sunnybrook & Womens Coll, Hlth Sci Ctr, Dept Med, Toronto, ON, Canada Univ Toronto Toronto ON Canada th Sci Ctr, Dept Med, Toronto, ON, Canada
Titolo Testata:
EUROPEAN RESPIRATORY JOURNAL
fascicolo: 3, volume: 17, anno: 2001,
pagine: 380 - 385
SICI:
0903-1936(200103)17:3<380:ICTRTR>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
OBSTRUCTIVE PULMONARY-DISEASE; HOSPITAL ADMISSION; UNITED-STATES; BUDESONIDE; MILD; READMISSION; SEVERITY; DEATH; INDEX;
Keywords:
asthma; hospitalization; inhaled corticosteroids; mortality;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Sin, DD Univ Alberta, Walter C Mackenzie Ctr 2E4 29, Dept Med, Edmonton, AB, Canada Univ Alberta Edmonton AB Canada , Dept Med, Edmonton, AB, Canada
Citazione:
D.D. Sin e J.V. Tu, "Inhaled corticosteroid therapy reduces the risk of rehospitalization and all-cause mortality in elderly asthmatics", EUR RESP J, 17(3), 2001, pp. 380-385

Abstract

Elderly patients with asthma have relatively high rates of hospitalizationand mortality. Although inhaled corticosteroids have been shown to improveoutcomes among younger patients with asthma, their usefulness in elderly patients has not been established. Therefore, a population-based study of patients 65 yrs of age or older, who have been hospitalized at least once with asthma in Ontario, Canada was conducted to determine the impact of inhaled corticosteroids on rehospitalization for asthma and all-cause mortality rates. Data from the Canadian Institute of Health Information was used to captureall patients 65 yrs of age and older mho mere hospitalized at least once, with the most responsible diagnosis of asthma in Ontario, Canada between fiscal year 1992 and 1996. This database mas then linked with drug claims, physician billing and mortality databases. In total, 6,254 consecutive elderly patients with asthma were identified. Sixty percent of these patients were given at least one prescription for inhaled corticosteroids within 90 days postdischarge from their index hospitalization for asthma. Users of inhaled corticosteroids postdischarge mere 29% (95% confidence interval (CI) 20%-38%) less Likely to be readmitted to hospital for asthma and 39% (95% CI, 20%-53%) less likely to experience all-cause mortality compared to those who did not receive these drugs postdischarge over a one year follow-up period. These findings suggest that inhaled corticosteroids are beneficial in reducing the risk for rehospitalization and all-cause mortality in elderly patients with asthma who have recently been hospitalized for their disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 22:57:09