Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Increased prevalence of obesity in narcoleptic patients and relatives
Autore:
Dahmen, N; Bierbrauer, J; Kasten, M;
Indirizzi:
Univ Mainz, Dept Psychiat, D-55131 Mainz, Germany Univ Mainz Mainz Germany D-55131 , Dept Psychiat, D-55131 Mainz, Germany Univ Frankfurt, Dept Psychiat, D-6000 Frankfurt, Germany Univ Frankfurt Frankfurt Germany D-6000 chiat, D-6000 Frankfurt, Germany
Titolo Testata:
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
fascicolo: 2, volume: 251, anno: 2001,
pagine: 85 - 89
SICI:
0940-1334(200104)251:2<85:IPOOIN>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
BODY-MASS INDEX; INCREASED FREQUENCY; RECEPTOR-2 GENE; HYPOCRETIN; DISORDER; MUTATION; OREXINS;
Keywords:
narcolepsy; obesity; body mass index; orexin; family study;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Dahmen, N Univ Mainz, Dept Psychiat, Untere Zahlbacher Str 8, D-55131 Mainz, Germany Univ Mainz Untere Zahlbacher Str 8 Mainz Germany D-55131 ermany
Citazione:
N. Dahmen et al., "Increased prevalence of obesity in narcoleptic patients and relatives", EUR ARCH PS, 251(2), 2001, pp. 85-89

Abstract

Increased Body Mass Indices (BMIs), increased prevalences of non insulin-dependent diabetes and sleep apnoe syndrome have been reported to be associated with narcolepsy. Our objective was to explore and possibly confirm the association of narcolepsy and increased BMI. In addition, we addressed the question whether increased BMIs also occur in relatives of narcoleptic patients. Together with narcolepsy-related clinical parameters we measured bodyweight and height of 132 narcoleptic patients who agreed to participate inour narcolepsy research program. In addition, 52 first degree relatives of22 index patients, mostly from multiplex families, were included in the study. Data were compared to published general population surveys, recently conducted in Germany and Switzerland as well as to collective of 104 psychiatric inpatients. Narcoleptic patients had significantly increased BMIs in comparison to general populations or psychiatric controls. BMIs of first degree relatives were lower than those of index patients but significantly higher than those found in the general population. BMIs were not related to symptom severity or to medication status. Thus, the elevated BMIs appeared not to be secondary to behavioral consequences of narcolepsy but may reflect a trait at least partially common to index patients and relatives.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 07:15:57