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Titolo:
Seasonal variation in host susceptibility and cycles of certain infectiousdiseases
Autore:
Dowell, SF;
Indirizzi:
Ctr Dis Control & Prevent, Atlanta, GA 30333 USA Ctr Dis Control & Prevent Atlanta GA USA 30333 ent, Atlanta, GA 30333 USA
Titolo Testata:
EMERGING INFECTIOUS DISEASES
fascicolo: 3, volume: 7, anno: 2001,
pagine: 369 - 374
SICI:
1080-6040(200105/06)7:3<369:SVIHSA>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
MENINGOCOCCAL DISEASE; IMMUNE FUNCTION; UNITED-STATES; MELATONIN; EPIDEMIOLOGY; INFLUENZA; PHOTOPERIOD; PATTERNS; VIRUS; POLIOMYELITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
60
Recensione:
Indirizzi per estratti:
Indirizzo: Dowell, SF Ctr Dis Control & Prevent, 1600 Clifton Rd NE,Mailstop C12, Atlanta, GA 30333 USA Ctr Dis Control & Prevent 1600 Clifton Rd NE,Mailstop C12 Atlanta GA USA 30333
Citazione:
S.F. Dowell, "Seasonal variation in host susceptibility and cycles of certain infectiousdiseases", EM INFECT D, 7(3), 2001, pp. 369-374

Abstract

Seasonal cycles of infectious diseases have been variously attributed to changes in atmospheric conditions, the prevalence or virulence of the pathogen, or the behavior of the host. Some observations about seasonality are difficult to reconcile with these explanations. These include the simultaneous appearance of outbreaks across widespread geographic regions of the same latitude; the detection of pathogens in the off-season without epidemic spread; and the consistency of seasonal changes, despite wide variations in weather and human behavior. In contrast, an increase in susceptibility of thehost population, perhaps linked to the annual light/dark cycle and mediated by the pattern of melatonin secretion, might account for many heretofore unexplained features of infectious disease seasonality. Ample evidence indicates that photoperiod-driven physiologic changes are typical in mammalian species, including some in humans. If such physiologic changes underlie human resistance to infectious diseases for large portions of the year and thechanges can be identified and modified, the therapeutic and preventive implications may be considerable.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/06/20 alle ore 01:14:52