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Titolo:
Surface activity in situ, in vivo, and in the captive bubble surfactometer
Autore:
Schurch, S; Bachofen, H; Possmayer, F;
Indirizzi:
Univ Calgary, Hlth Sci Ctr, Dept Physiol & Biophys, Resp Res Grp, Calgary,AB T2N 4N1, Canada Univ Calgary Calgary AB Canada T2N 4N1 es Grp, Calgary,AB T2N 4N1, Canada Univ Hosp Bern, DMLL, Div Pneumol, CH-3010 Bern, Switzerland Univ Hosp Bern Bern Switzerland CH-3010 eumol, CH-3010 Bern, Switzerland Univ Western Ontario, Dept Obstet Gynaecol & Biochem, London, ON, Canada Univ Western Ontario London ON Canada ecol & Biochem, London, ON, Canada
Titolo Testata:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY
fascicolo: 1, volume: 129, anno: 2001,
pagine: 195 - 207
SICI:
1095-6433(200105)129:1<195:SAISIV>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALVEOLAR LINING LAYER; RESPIRATORY-DISTRESS SYNDROME; FETAL LUNG MATURITY; PULMONARY SURFACTANT; RECOIL PRESSURE; CONTACT-ANGLE; RABBIT LUNGS; TENSION; AREA; VOLUME;
Keywords:
film structure; lung surfactant; microbubble clicking stability; multilayers;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Schurch, S Univ Calgary, Hlth Sci Ctr, Dept Physiol & Biophys, Resp Res Grp, 3330 Hosp Dr NW, Calgary, AB T2N 4N1, Canada Univ Calgary 3330 Hosp Dr NW Calgary AB Canada T2N 4N1 , Canada
Citazione:
S. Schurch et al., "Surface activity in situ, in vivo, and in the captive bubble surfactometer", COMP BIOC A, 129(1), 2001, pp. 195-207

Abstract

For studies of the mechanical effects of lung surfactants, the captive bubble surfactometer (CBS) combines the advantages of the continuous film of Patties bubbles with the feasibility of the Langmuir-Wilhelmy balance to produce surface tension-area hysteresis loops. The CBS allows the compression of films to very low and stable surface tensions of 1-2 mN/m. Such low and stable surface tensions are in line with results obtained from pressure-volume studies on excised lungs. In addition, the CBS is useful to test other essential physical properties of the surfactant system, including: (1) rapid film formation (within seconds) through adsorption from the hypophase, (2) low film compressibility with a fall in surface tension to very low (< 2 mN/m) values during surface compression; and (3) effective replenishment ofthe surface film on expansion by the incorporation of surfactant material from material associated with the surface (the surface associated surfactant reservoir). Morphological observations of films fixed in situ or in vitroreveal frequently their multilayered structure, which is consistent with the concept of the surface reservoir. The deviation of the bubbles from a Laplacian shape at very low surface tension and the morphological observations suggest that the surfactant film cannot be considered a simple monolayer. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 04:12:23