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Titolo:
Travel and the introduction of human immunodeficiency virus type 1 non-B subtype genetic forms into western countries
Autore:
Thomson, MM; Najera, R;
Indirizzi:
Inst Salud Carlos III, Ctr Nacl Biol Fundamental, Area Patogenia Viral, Madrid 28220, Spain Inst Salud Carlos III Madrid Spain 28220 enia Viral, Madrid 28220, Spain
Titolo Testata:
CLINICAL INFECTIOUS DISEASES
fascicolo: 12, volume: 32, anno: 2001,
pagine: 1732 - 1737
SICI:
1058-4838(20010615)32:12<1732:TATIOH>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIV-1 SUBTYPES; RISK BEHAVIOR; RECOMBINANT FORM; HOMOSEXUAL MEN; BUENOS-AIRES; DRUG-USERS; GROUP-O; INFECTION; PREVALENCE; THAILAND;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Najera, R Inst Salud Carlos III, Ctr Nacl Biol Fundamental, Area PatogeniaViral, Ctra Majadahonda Pozuelo,Km 2, Madrid 28220, Spain Inst Salud Carlos III Ctra Majadahonda Pozuelo,Km 2 Madrid Spain 28220
Citazione:
M.M. Thomson e R. Najera, "Travel and the introduction of human immunodeficiency virus type 1 non-B subtype genetic forms into western countries", CLIN INF D, 32(12), 2001, pp. 1732-1737

Abstract

Both high mutation rates and recombination contribute to the genetic diversity of human immunodeficiency virus type 1 (HIV-1). Among viruses of the main group, which are responsible for the HIV-1 pandemic, 21 circulating genetic forms have been reported, 11 of which are recombinant between greater than or equal to2 subtypes. In Western Europe and the Americas, the HIV-1 epidemic is largely dominated by B subtype viruses; however, infections withdiverse non-B subtype genetic forms are increasingly being recognized. In Western Europe and North America, most of them have been identified in immigrants or travelers returning from areas with high HIV-1 prevalence, mainlyfrom sub-Saharan Africa and Southeast Asia, where non-B subtype genetic forms predominate, but propagation within other groups has been reported in some Western countries. This may have implications for prophylactic and therapeutic strategies and, by bringing in contact different genetic forms, mayfavor the generation of novel recombinant viruses. Travelers from different categories-including immigrants, military personnel, seamen, tourists, expatriates, diplomats, and businessmen-may be at risk of transporting HIV non-B subtype genetic forms to Western countries.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 07:56:02