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Titolo:
COST COMPARISON OF SINGLE DAILY IV-DOSES OF CEFTRIAXONE VERSUS CONTINUOUS-INFUSION OF CEFOTAXIME
Autore:
HITT CM; NIGHTINGALE CH; QUINTILIANI R; NICOLAU DP;
Indirizzi:
MAYO MED CTR,HOSP PHARM SERV,1216 2ND ST SW ROCHESTER MN 55902 HARTFORD HOSP,DEPT MED,DIV INFECT DIS HARTFORD CT 06115 HARTFORD HOSP,DEPT PHARM HARTFORD CT 06115
Titolo Testata:
American journal of health-system pharmacy
fascicolo: 14, volume: 54, anno: 1997,
pagine: 1614 - 1618
SICI:
1079-2082(1997)54:14<1614:CCOSDI>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
SERIOUS BACTERIAL-INFECTIONS; PHARMACOKINETICS; CEFTAZIDIME; THERAPY; MODEL;
Keywords:
CEFOTAXIME SODIUM; CEFTRIAXONE SODIUM; CEPHALOSPORINS; COSTS; DOSAGE SCHEDULES; DRUG ADMINISTRATION; DRUG ADMINISTRATION SYSTEMS; DRUG COMPARISONS; ECONOMICS; INJECTIONS; NURSES; PHARMACISTS, HOSPITALS; TIME STUDIES; WORKLOAD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
C.M. Hitt et al., "COST COMPARISON OF SINGLE DAILY IV-DOSES OF CEFTRIAXONE VERSUS CONTINUOUS-INFUSION OF CEFOTAXIME", American journal of health-system pharmacy, 54(14), 1997, pp. 1614-1618

Abstract

The costs of administering ceftriaxone 1 g in a once-daily 30-minute infusion were compared with the costs of administering cefotaxime 2 g/day (with an additional 1 g given on day 1) by continuous intravenous infusion. Time and motion studies were conducted to determine the pharmacy and nursing labor required to prepare and administer the intermittent and continuously infused antimicrobials. Mean times were multiplied by the mean New England hourly wage for pharmacy technicians, pharmacists, and nurses to determine the total labor costs of each regimen. Hospital acquisition costs of items used in preparing antimicrobial doses for administration by each method were also compared. Wholesale acquisition costs of the two drugs were used in the analysis. Labor costs were higher for the continuously infused antimicrobial because of the additional nursing time required for monitoring. Supply costs were greater for continuous infusion. Drug acquisition cost was the major component of the overall cost of therapy and was lower for continuous infusion. A cost analysis showed that continuous i.v. infusion of cefotaxime 2 g/day was less expensive from day 2 onward than intermittent daily i.v. doses of ceftriaxone 1 g.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 14:10:11