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Titolo:
Angiogenesis (clinical trials)
Autore:
Laham, R;
Indirizzi:
Harvard Univ, Sch Med, Angiogenesis Res Ctr, BIDMC, Boston, MA 02215 USA Harvard Univ Boston MA USA 02215 sis Res Ctr, BIDMC, Boston, MA 02215 USA
Titolo Testata:
CANADIAN JOURNAL OF CARDIOLOGY
, volume: 17, anno: 2001, supplemento:, A
pagine: 29A - 32A
SICI:
0828-282X(200105)17:<29A:A(T>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
FIBROBLAST-GROWTH-FACTOR; CHRONIC MYOCARDIAL-ISCHEMIA; INCOMPLETE REVASCULARIZATION; BYPASS SURGERY; GENE-THERAPY; IN-VITRO; DELIVERY; DISEASE; MODEL; PIGS;
Keywords:
angiogenesis; clinical trials; collateral circulation; coronary disease; growth substances; ischemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Laham, R Harvard Univ, Sch Med, Angiogenesis Res Ctr, BIDMC, 330 BrooklineAve, Boston, MA 02215 USA Harvard Univ 330 Brookline Ave Boston MA USA 02215 , MA 02215 USA
Citazione:
R. Laham, "Angiogenesis (clinical trials)", CAN J CARD, 17, 2001, pp. 29A-32A

Abstract

Therapeutic angiogenesis may play a role in the treatment of patients withvascular disease who have no other treatment option (those who are not candidates for bypass surgery or angioplasty). The first published clinical trial results appeared in 1998 and additional trials have since been completed or are ongoing. Results of several of these trials are reviewed. Studies of angiogenesis with basic fibroblast growth factor and human vascular endothelial growth factor suggest that these growth factors can induce functionally significant angiogenesis. Evolving delivery modalities and strategies are also highlighted.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 13:00:10