Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Prevalence and genetic variants of Hepatitis GB-C/HG and TT viruses in Gabon, equatorial Africa
Autore:
Tuveri, R; Perret, JL; Delaporte, E; Nguemby-Mbina, C; DAllones, LR; Henzel, D; Faivre, D; Scarpa, B; Contu, P; Colombo, M; Thiers, V; Brechot, C; Larouze, B;
Indirizzi:
Necker Univ, THIERS, Natl Reference Ctr Viral Hepatitis, Necker & Pasteru Inst, F-75730 Paris 15, France Necker Univ Paris France 15 ker & Pasteru Inst, F-75730 Paris 15, France Inst Pasteur, Paris, France Inst Pasteur Paris FranceInst Pasteur, Paris, France Univ Cagliari, Dept Publ Hlth, I-09100 Cagliari, Italy Univ Cagliari Cagliari Italy I-09100 Publ Hlth, I-09100 Cagliari, Italy Principal Hosp, Med Serv, Dakar, Senegal Principal Hosp Dakar SenegalPrincipal Hosp, Med Serv, Dakar, Senegal Retrovirus Lab, Montpellier, France Retrovirus Lab Montpellier FranceRetrovirus Lab, Montpellier, France Cent Hosp Libreville, Med Serv, Libreville, Gabon Cent Hosp Libreville Libreville Gabon ille, Med Serv, Libreville, Gabon INSERM, U444, Fac Med Bichat & St Antoine, Paris, France INSERM Paris France M, U444, Fac Med Bichat & St Antoine, Paris, France Maggiore Hosp, Inst Internal Med, IRCCS, I-20122 Milan, Italy Maggiore Hosp Milan Italy I-20122 ernal Med, IRCCS, I-20122 Milan, Italy Necker Univ, U370, Natl Inst Hlth & Med Res, F-75730 Paris 15, France Necker Univ Paris France 15 nst Hlth & Med Res, F-75730 Paris 15, France Hop Necker Enfants Malad, Liver Unit, F-75747 Paris 15, France Hop Necker Enfants Malad Paris France 15 Unit, F-75747 Paris 15, France
Titolo Testata:
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
fascicolo: 3-4, volume: 63, anno: 2000,
pagine: 192 - 198
SICI:
0002-9637(200009/10)63:3-4<192:PAGVOH>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
NON-B-HEPATITIS; HIGH-RISK GROUPS; A-G HEPATITIS; DNA VIRUS; C VIRUS; BLOOD-DONORS; POSTTRANSFUSION HEPATITIS; PHYLOGENETIC ANALYSIS; UNKNOWN ETIOLOGY; MOLECULAR-CLONING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
50
Recensione:
Indirizzi per estratti:
Indirizzo: Tuveri, R Necker Univ, THIERS, Natl Reference Ctr Viral Hepatitis, Necker & Pasteru Inst, F-75730 Paris 15, France Necker Univ Paris France 15 eru Inst, F-75730 Paris 15, France
Citazione:
R. Tuveri et al., "Prevalence and genetic variants of Hepatitis GB-C/HG and TT viruses in Gabon, equatorial Africa", AM J TROP M, 63(3-4), 2000, pp. 192-198

Abstract

The distribution of Hepatitis GB-C/HG (GB-C/HG) and TT viruses (TTV) infections was investigated in selected populations from Gabon using Polymerase Chain Reaction (PCR) and Enzyme Linked Immunosorbent Assay (ELISA) for anti-Envelop 2 (anti-E2) GBV-C/HGV antibodies. Among pregnant women, 29 of 229 (12.6%) were Hepatitis GB virus-C and Hepatitis G virus (GBV-C/HGV) RNA positive (+) and 32 of 81 (39.5%) anti-E2 + versus 8 of 39 (20.5%) TTV DNA +. Among sickle cell anemia patients, 9.7% (3/31) were GBV-C/HGV RNA + versus 22.5% (7/31) TTV DNA +. For tuberculosis patients, the figures were 11.5% (4/35) and 0%. A study of hepatocellular carcinoma cases (n = 27) versus controls (n = 66) did not show significant differences Tol GBV-C/HGV RNA (10.7% versus 12.1%) and TTV DNA (44.4% versus 30.3%). According to phylogeneticanalysis, the 15 GBV-C/HGV strains investigated clustered in group 1, the most common in sub-Saharan Africa whereas TTV sequences (n = 4) mostly clustered in genotypes G1 and one close to genotype G3. In the Gabonese populations investigated, GBV-C/HGV and TTV infections were highly endemic. These data are consistent with the low pathogenicity of these agents.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 09:17:04