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Titolo:
Focal nodular hyperplasia and hepatocellular adenoma of the liver: Differentiation with multiphasic helical CT
Autore:
Ruppert-Kohlmayr, AJ; Uggowitzer, MM; Kugler, C; Zebedin, D; Schaffler, G; Ruppert, GS;
Indirizzi:
Univ Hosp Graz, Dept Radiol, A-8036 Graz, Austria Univ Hosp Graz Graz Austria A-8036 az, Dept Radiol, A-8036 Graz, Austria Doors Knowledge, A-8410 Wildon, Austria Doors Knowledge Wildon Austria A-8410 Knowledge, A-8410 Wildon, Austria
Titolo Testata:
AMERICAN JOURNAL OF ROENTGENOLOGY
fascicolo: 6, volume: 176, anno: 2001,
pagine: 1493 - 1498
SICI:
0361-803X(200106)176:6<1493:FNHAHA>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPATIC ADENOMA; DYNAMIC CT; TUMORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Ruppert-Kohlmayr, AJ Univ Hosp Graz, Dept Radiol, Auenbruggerpl 9, A-8036 Graz, Austria Univ Hosp Graz Auenbruggerpl 9 Graz Austria A-8036 a
Citazione:
A.J. Ruppert-Kohlmayr et al., "Focal nodular hyperplasia and hepatocellular adenoma of the liver: Differentiation with multiphasic helical CT", AM J ROENTG, 176(6), 2001, pp. 1493-1498

Abstract

OBJECTIVE. Differences of attenuation and enhancement patterns in focal nodular hyperplasia and hepatocellular adenoma were evaluated and quantified using triphasic single-slice helical CT. MATERIALS AND METHODS. Forty-five histologically proven focal nodular hyperplasias in 27 patients and 18 hepatocellular adenomas in six patients wereexamined with helical CT. Quantitative evaluation included the following: attenuation of lesions, scar, and liver parenchyma during unenhanced, arterial (20 sec after injection), and portal venous phases (70 sec after injection); relative enhancement of lesions and liver (the ratio between attenuation in arterial phase and portal venous phase, respectively, and attenuation in unenhanced phase); and the prevalence of scar and its central vessel in focal nodular hyperplasia. RESULTS. The study showed no significant difference between mean attenuation values of focal nodular hyperplasia (mean +/- SD, 51.2 +/- 5.9 H) and hepatocellular adenoma (mean +/- SD, 56.3 +/- 7.8 H) in the unenhanced phase. In the arterial phase attenuation values were significantly higher in focal nodular hyperplasia (mean +/- SD, 117.9 +/- 15.1 H) than in hepatocellular adenoma (mean +/- SD, 80.1 +/- 10.5 H): In the portal venous phase no significant differences in attenuation values were detected between focal nodular hyperplasia (mean +/- SD, 112.1 +/- 20.4 H) and hepatocellular adenoma (mean +/- SD, 110.2 +/- 12.9 H). For enhancement parameter thresholds separating focal nodular hyperplasia from hepatocellular adenoma, the following were found: the relative enhancement was higher in 100% of the focal nodular hyperplasias and lower than or equal to 1.6 (accuracy, 96%) in 87% of thehepatocellular adenomas. CONCLUSION. Triphasic helical CT combined with quantitative evaluation of liver lesions offers the possibility of detecting differences in liver lesions that are visually similar on CT. The attenuation and relative enhancement in the arterial phase show significant differences that make accurate differentiation between focal nodular hyperplasia and hepatocellular adenoma possible.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 19:33:57