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Titolo:
Cost considerations in sedation, analgesia, and neuromuscular blockade in the intensive care unit
Autore:
Kress, JP; Hall, JB;
Indirizzi:
Univ Chicago, Sect Pulm & Crit Care, Dept Med, Chicago, IL 60637 USA Univ Chicago Chicago IL USA 60637 t Care, Dept Med, Chicago, IL 60637 USA
Titolo Testata:
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 2, volume: 22, anno: 2001,
pagine: 199 - 209
SICI:
1069-3424(2001)22:2<199:CCISAA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
CRITICALLY-ILL PATIENTS; RESPIRATORY-DISTRESS SYNDROME; MECHANICAL VENTILATION; STATUS-ASTHMATICUS; BLOCKING-AGENTS; PERMISSIVE HYPERCAPNIA; NOSOCOMIAL PNEUMONIA; MUSCLE WEAKNESS; MIDAZOLAM; PROPOFOL;
Keywords:
sedation; benzodiazepines; opiates; neuromuscular blocking agents; critical care; costs and cost analysis;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
68
Recensione:
Indirizzi per estratti:
Indirizzo: Hall, JB Univ Chicago, Sect Pulm & Crit Care, Dept Med, MC 6026, Chicago, IL 60637 USA Univ Chicago MC 6026 Chicago IL USA 60637 , Chicago, IL 60637 USA
Citazione:
J.P. Kress e J.B. Hall, "Cost considerations in sedation, analgesia, and neuromuscular blockade in the intensive care unit", SEM RESP CR, 22(2), 2001, pp. 199-209

Abstract

Sedation of critically ill patients is a costly endeavor. Costs of commonly used intensive care unit (ICU) sedatives range from pennies to more than $500 per day. Although the agents account for some of this expense, complications related to the use of these drugs in the ICU produce even greater costs. Prolongation of mechanical ventilation and length of stay are some of the common complications resulting from non-ideal use of these drugs. Sedative agents also impair neurological evaluation in many critically ill patients, which may mask detection of acute delirium resulting from intercurrentillness or intracranial catastrophes and can lead to excessive diagnostic testing. Opiates may result in gastrointestinal dysfunction with resulting malnutrition and perhaps bacterial translocation and sepsis, Neuromuscular blocking agents may cause prolonged paralysis and disability in critically ill patients who receive them. Simple dosing strategies based on pharmacological principles may decrease the incidence of these costly problems.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 07:06:11