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Titolo:
Use of sedative medications in the intensive care unit
Autore:
Nasraway, SA;
Indirizzi:
Tufts Univ, Sch Med, Tufts New England Med Ctr, Dept Surg, Boston, MA 02111 USA Tufts Univ Boston MA USA 02111 d Med Ctr, Dept Surg, Boston, MA 02111 USA
Titolo Testata:
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 2, volume: 22, anno: 2001,
pagine: 165 - 174
SICI:
1069-3424(2001)22:2<165:UOSMIT>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
CRITICALLY-ILL PATIENTS; LONG-TERM SEDATION; MECHANICAL VENTILATION; CONTINUOUS-INFUSION; PROPOFOL INFUSION; ALPHA(2)-ADRENERGIC AGONISTS; INTRAVENOUS ANALGESIA; WITHDRAWAL SYNDROME; STATUS EPILEPTICUS; DELIRIUM-TREMENS;
Keywords:
dexmedetomidine; benzodiazepines; propofol;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
67
Recensione:
Indirizzi per estratti:
Indirizzo: Nasraway, SA Tufts Univ, Sch Med, Tufts New England Med Ctr, Dept Surg, 750 Washington St,Box 4630, Boston, MA 02111 USA Tufts Univ 750 Washington St,Box 4630 Boston MA USA 02111 USA
Citazione:
S.A. Nasraway, "Use of sedative medications in the intensive care unit", SEM RESP CR, 22(2), 2001, pp. 165-174

Abstract

Current choices for sustained sedation in the critically ill include the benzodiazepines, the opiates, and propofol. Each of these groups of medications has their particular benefits: benzodiazepines provide the greatest amnesia, opiates are the only agents to provide analgesia, and propofol is themost easily titratable and the least likely to excessively accrue. The literature seems to favor propofol over the benzodiazepines as the most cost-effective solution to sustained sedation. A newly approved agent, dexmedetomidine, holds promise as a continuous infusion that can provide both anxiolysis and analgesia, but without the ventilatory depression seen in the otherclasses of sedatives. Further research is needed to determine the role of dexmedetomidine in the ICU The emerging standard of care for sustained sedation is the use of standardized protocols, formulated with the help of clinical practice guidelines, and titrated with the guidance of sedation monitoring.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 22:00:49