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Titolo:
Memory impairment differs in frontotemporal dementia and Alzheimer's disease
Autore:
Pasquier, F; Grymonprez, L; Lebert, F; Van der Linden, M;
Indirizzi:
CHU Lille, Dept Neurol, Memory Ctr, F-59037 Lille, France CHU Lille Lille France F-59037 Neurol, Memory Ctr, F-59037 Lille, France Univ Geneva, Cognit Psychopathol Unit, Geneva, Switzerland Univ Geneva Geneva Switzerland t Psychopathol Unit, Geneva, Switzerland
Titolo Testata:
NEUROCASE
fascicolo: 2, volume: 7, anno: 2001,
pagine: 161 - 171
SICI:
1355-4794(2001)7:2<161:MIDIFD>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
FRONTAL-LOBE DEGENERATION; CLINICAL DIAGNOSTIC-CRITERIA; EXPLICIT MEMORY; PICKS-DISEASE; HUNTINGTONS-DISEASE; NEUROPSYCHOLOGICAL FINDINGS; CHOLINERGIC BLOCKADE; SEMANTIC DEMENTIA; PRIMING DEFICITS; IMPLICIT MEMORY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
94
Recensione:
Indirizzi per estratti:
Indirizzo: Pasquier, F CHU Lille, Dept Neurol, Memory Ctr, F-59037 Lille, France CHU Lille Lille France F-59037 ry Ctr, F-59037 Lille, France
Citazione:
F. Pasquier et al., "Memory impairment differs in frontotemporal dementia and Alzheimer's disease", NEUROCASE, 7(2), 2001, pp. 161-171

Abstract

The aim of this study was to assess short-term and long-term explicit memory and implicit memory in frontotemporal dementia (FTD; frontal variant) and to compare FTD and Alzheimer's disease (AD) patients with similar severity of dementia. Fifteen FTD patients [mean age: 68 years; Mini-Mental State (MMS): 24], 30 probable AD patients (mean age: 72 years; MMS: 23) and 12 healthy subjects participated in the study. The three groups were comparable in terms of gender and educational level. Short-term memory was assessed with the digit span and Corsi block-tapping tests. Explicit verbal memory wasassessed with the Grober and Buschke test, and implicit memory with a verbal priming task and a fragmented picture test. FTD patients demonstrated a genuine memory deficit with impaired digit span, encoding deficit and retrieval strategy difficulties, but preserved implicit verbal and visual priming. Memory patterns differed in AD and FTD: short-term memory and free recall were similarly decreased in FTD and AD but cues provided more benefit to FTD than to AD; encoding was more impaired and the forgetting rate was faster in AD than in FTD; priming was lower in AD than in FTD. AD patients withclinical and imaging frontal lobe dysfunction tended to have lower memory performance and to differ even more from FTD patients than AD patients without frontal lobe dysfunction.

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Documento generato il 25/01/20 alle ore 19:23:53