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Titolo:
Determination of response latency and its application to normalization of cross-correlation measures
Autore:
Baker, SN; Gerstein, GL;
Indirizzi:
Univ Cambridge, Dept Anat, Cambridge CB2 3DY, England Univ Cambridge Cambridge England CB2 3DY nat, Cambridge CB2 3DY, England Univ Penn, Dept Neurosci, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 Neurosci, Philadelphia, PA 19104 USA
Titolo Testata:
NEURAL COMPUTATION
fascicolo: 6, volume: 13, anno: 2001,
pagine: 1351 - 1377
SICI:
0899-7667(200106)13:6<1351:DORLAI>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
SINGLE UNITS; CORTICAL-NEURONS; FRONTAL-CORTEX; DISCHARGE; PATTERNS; INFORMATION; MODULATION; CELLS; SYNCHRONIZATION; CONNECTIVITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Engineering, Computing & Technology
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Baker, SN Univ Cambridge, Dept Anat, Downing St, Cambridge CB2 3DY, England Univ Cambridge Downing St Cambridge England CB2 3DY DY, England
Citazione:
S.N. Baker e G.L. Gerstein, "Determination of response latency and its application to normalization of cross-correlation measures", NEURAL COMP, 13(6), 2001, pp. 1351-1377

Abstract

It is often of interest experimentally to assess how synchronization between two neurons changes following a stimulus or other behaviorally relevant marker. The joint peristimulus time histogram (JPSTH) achieves this, but assumes that changes in the cells' firing rate following the stimulus are stereotyped from one sweep to the next. Erroneous results can be generated if this is not the case. We here present a method to assess whether there are variations in response latency or amplitude from sweep to sweep. We then describe how the effects of response latency variation can be mitigated by realigning sweeps to their individual latencies. Three methods of detecting response latency are presented and their performance compared on simulated data. Finally, the effect on the JPSTH of sweep realignment using detected latencies is illustrated.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 04:01:40