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Titolo:
Diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI): additional methods for psychiatric research
Autore:
Braus, DF; Tost, H; Hirsch, JG; Gass, A;
Indirizzi:
NMR Forsch Zent Inst Seel Gesundheit, D-68072 Mannheim, Germany NMR ForschZent Inst Seel Gesundheit Mannheim Germany D-68072 m, Germany Univ Klinikums Mannheim, NMR Forsch Neurol Klin, Mannheim, Germany Univ Klinikums Mannheim Mannheim Germany Neurol Klin, Mannheim, Germany
Titolo Testata:
NERVENARZT
fascicolo: 5, volume: 72, anno: 2001,
pagine: 384 - 390
SICI:
0028-2804(200105)72:5<384:DTI(AF>2.0.ZU;2-V
Fonte:
ISI
Lingua:
GER
Soggetto:
WHITE-MATTER; ALZHEIMERS-DISEASE; AUDITORY HALLUCINATIONS; CORPUS-CALLOSUM; HUMAN BRAIN; SCHIZOPHRENIA; MRI; ANISOTROPY; ACTIVATION; CONTRAST;
Keywords:
functional magnetic resonance imaging (fMRI) diffusion tensor imaging (DTI); anisotropy; psychiatry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Braus, DF NMR Forsch Zent Inst Seel Gesundheit, Postfach 122120, D-68072 Mannheim, Germany NMR Forsch Zent Inst Seel Gesundheit Postfach 122120 Mannheim Germany D-68072
Citazione:
D.F. Braus et al., "Diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI): additional methods for psychiatric research", NERVENARZT, 72(5), 2001, pp. 384-390

Abstract

In psychiatric research, there is a growing interest in the microstructural and functional characteristics of brain networks, which often form the basis of current etiological concepts. As a result of novel magnetic resonance imaging techniques, the pathogenic characteristics of neuronal activity and connectivity can be examined in a noninvasive, safe, and repeatable manner. Functional magnetic resonance imaging (fMRI) uses blood oxygenation level-dependent (BOLD) measures for identifying the gray matter contribution to cognition. Diffusion tensor imaging(DTI) reveals the course and structural integrity of white matter projections. Because DTI does not require special motivation and performance, group differences in psychiatry are more easily interpreted in terms of underlying pathology. To date few studies have tried to investigate both, i.e. dynamic and microstructural data in the sense of a modern multi-dimensional investigation approach. The combination ofboth techniques, however, seems to offer a promising vehicle to further extent our current understanding of mental disorders and to identify populations at risk. In addition to addressing findings in psychiatric research, the present article presents a technical overview of DTI and examines the limitations and potential applications of both techniques.

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Documento generato il 18/09/20 alle ore 11:14:34