Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Onset, time course, and persistence of increased haemodialysis-induced breath isoprene emission
Autore:
Trovarelli, G; Brunori, F; De Medio, GE; Timio, M; Lippi, G; Pelli, MA; Capodicasa, E;
Indirizzi:
Univ Perugia, Sch Med, Dept Clin & Expt Med, I-06100 Perugia, Italy Univ Perugia Perugia Italy I-06100 in & Expt Med, I-06100 Perugia, Italy Univ Perugia, Sch Med, Dept Emergency & Gen Surg, I-06100 Perugia, Italy Univ Perugia Perugia Italy I-06100 cy & Gen Surg, I-06100 Perugia, Italy Univ Perugia, Sch Med, Inst Med Biochem & Chem, I-06100 Perugia, Italy Univ Perugia Perugia Italy I-06100 iochem & Chem, I-06100 Perugia, Italy SG Battista Gen Hosp, Nephrol & Dialysis Unit, Foligno, Italy SG Battista Gen Hosp Foligno Italy hrol & Dialysis Unit, Foligno, Italy
Titolo Testata:
NEPHRON
fascicolo: 1, volume: 88, anno: 2001,
pagine: 44 - 47
SICI:
0028-2766(200105)88:1<44:OTCAPO>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMA MEVALONATE; METABOLISM; EXCRETION; AIR;
Keywords:
isoprene; haemodialysis; human breath;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Capodicasa, E Univ Perugia, Sch Med, Dept Clin & Expt Med, Via Brunamonti,I-06100 Perugia, Italy Univ Perugia Via Brunamonti Perugia Italy I-06100 ia, Italy
Citazione:
G. Trovarelli et al., "Onset, time course, and persistence of increased haemodialysis-induced breath isoprene emission", NEPHRON, 88(1), 2001, pp. 44-47

Abstract

Recent findings of increased isoprene emission in the exhaled breath of patients undergoing haemodialysis and experimental evidence of the potential toxic and cancerogenic effects of isoprene hydrocarbon led us to assess howlong haemodialysis patients are exposed to how much isoprene after a single haemodialysis session. Patients with end-stage renal failure on regular 4-hour (from 08.00 to 12.00 h) maintenance haemodialysis three times weekly were monitored. The breath isoprene content was analyzed by gas chromatography. Intrapatient evaluations were performed by collecting samples before, during, and immediately after the haemodialysis session, during the following hours, and on the following nondialysis day. The breath isoprene contentincreased in all patients. Isoprene overproduction showing a biphasic pattern was first detected soon after the dialysis session ended. These data show that haemodialyzed patients seem to be consistently exposed to high endogenous isoprene concentrations. The mechanisms and implications of this endogenous isoprene overproduction need to be elucidated with regard to the mevalonic pathway and in the physiopathological setting of the uraemia-dialysis syndrome. Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 10:35:52